4.6 Article

Direct Amination of Arenes with Azodicarboxylates Catalyzed by Bisulfate Salt/HFIP Association

Journal

ACS OMEGA
Volume 4, Issue 5, Pages 8960-8966

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsomega.9b00781

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Funding

  1. China Scholarship Council (CSC)

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A mild and efficient amination of arenes with azodicarboxylates using potassium bisulfate (KHSO4) as the catalyst in 1,1,1,3,3,3-hexafluoro-2-propanol has been developed. This protocol allowed the amination of a broad range of arenes leading to corresponding hydrazides in good to excellent yields.

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