Journal
NANO CONVERGENCE
Volume 6, Issue -, Pages -Publisher
SPRINGER
DOI: 10.1186/s40580-019-0183-4
Keywords
Polyelectrolyte; Gold nanoparticles; Nanoparticles; Gold; Biomedical
Funding
- Australian Institute of Nuclear Science and Engineering (AINSE Ltd) (Award-PGRA)
- Australian Government Research Training Program
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Surface modified gold nanoparticles are becoming more and more popular for use in biomaterials due to the possibility for specific targeting and increased biocompatibility. This review provides a summary of the recent literature surrounding polyelectrolyte coatings on spherical gold nanoparticles and their potential biomedical applications. The synthesis and layer-by layer coating approach are briefly discussed together with common characterisation methods. The potential applications and recent developments in drug delivery, gene therapy, photothermal therapy and imaging are summarized as well as the effects on cellular uptake and toxicity. Finally, the future outlook for polyelectrolyte coated gold nanoparticles is explored, focusing on their use in biomedicine.
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