Journal
MICROORGANISMS
Volume 7, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/microorganisms7060177
Keywords
Mycobacterium tuberculosis complex; carbon metabolism; macrophages; tuberculosis; cholesterol; fatty acids
Categories
Funding
- NIH [AI130018]
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Pathogenic mycobacteria are known for their ability to maintain persistent infections in various mammals. The canonical pathogen in this genus is Mycobacterium tuberculosis and this bacterium is particularly successful at surviving and replicating within macrophages. Here, we will highlight the metabolic processes that M. tuberculosis employs during infection in macrophages and compare these findings with what is understood for other pathogens in the M. tuberculosis complex.
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