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Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain
FT Huang et al.
MOLECULAR CELL (2006)
Ubiquitylation and cell signaling
K Haglund et al.
EMBO JOURNAL (2005)
VHLprotein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1α
ZB Li et al.
EMBO REPORTS (2005)
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
SMB Nijman et al.
MOLECULAR CELL (2005)
A dynamic role of HAUSP in the p53-Mdm2 pathway
MY Li et al.
MOLECULAR CELL (2004)
Hypoxia-inducible factor-1 and oncogenic signalling
JI Bárdos et al.
BIOESSAYS (2004)
Siah2 regulates stability of prolyl-hydroxylases, controls HIF1α abundance, and modulates physiological responses to hypoxia
K Nakayama et al.
CELL (2004)
Inactivating mutations of the Siah-1 gene in gastric cancer
CJ Kim et al.
ONCOGENE (2004)
Hypoxia enhances metastatic efficiency by up-regulating Mdm2 in KHT cells and increasing resistance to apoptosis
L Zhang et al.
CANCER RESEARCH (2004)
Siah - New players in the cellular response to hypoxia
K Nakayama et al.
CELL CYCLE (2004)
Non-traditional functions of ubiquitin and ubiquitin-binding proteins
JD Schnell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1α expression in renal cell carcinomas
X Na et al.
JOURNAL OF UROLOGY (2003)
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
K Haglund et al.
NATURE CELL BIOLOGY (2003)
Orchestrating nuclear functions: ubiquitin sets the rhythm
I Bach et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
The UCH-L1 gene encodes two opposing enzymatic activities that affect α-synuclein degradation and Parkinson's disease susceptibility
YC Liu et al.
CELL (2002)
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part 1: Creatine kinase bb, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1
A Castegna et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
D Lando et al.
SCIENCE (2002)
Expression of the SART1 tumor-rejection antigens in colorectal cancers
T Sasatomi et al.
DISEASES OF THE COLON & RECTUM (2000)
Ubiquitin in chains
CM Pickart
TRENDS IN BIOCHEMICAL SCIENCES (2000)
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein
M Ohh et al.
NATURE CELL BIOLOGY (2000)
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
U Schubert et al.
NATURE (2000)