Journal
ARCHIVES OF VIROLOGY
Volume 161, Issue 6, Pages 1723-1727Publisher
SPRINGER WIEN
DOI: 10.1007/s00705-016-2827-6
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Funding
- China Mega-Project on Infectious Disease Prevention [2013ZX10004-605, 2013ZX10004-607, 2013ZX10004-217, 2011ZX10004-001]
- National Hi-Tech Research and Development (863) Program of China [2014AA021402, 2012AA022-003, 2015AA020108]
- National Natural Science Foundation of China [81572045, 81273138]
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A new flavivirus, Xishuangbanna flavivirus (XFV), infecting Aedes albopictus mosquitoes in Yunnan Province, China, was isolated and sequenced. The single-stranded RNA genome of 10,884 nt contained two open reading frames (ORFs) encoding the polyprotein and FIFO. The genome had a maximum nucleotide sequence identity of 65 % to Parramatta River virus with coverage of only 27 %. Phylogenetic analysis suggested that this virus is most closely related to recognized classical insect-specific flaviviruses (cISF) and most likely has a similar host range. Sequence comparisons and phylogenetic analysis demonstrated that XFV is a new member of the genus Flavivirus.
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