Journal
JOURNAL OF CLINICAL MEDICINE
Volume 8, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/jcm8071016
Keywords
early intervention; cerebral palsy; development; other neurological disorder; gross motor function; upper limb function; communication
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Funding
- Swedish Research Council [521-2013-3096, 2016-01009]
- Stockholm City Council [1411-1372, 20150153]
- Stiftelsen Frimurare-Barnhuset
- Sunnerdahls Handikappfond
- Stiftelsen Olle Engkvist Byggmastare
- Stiftelsen Promobilia
- Norrbacka-Eugeniastiftelsen
- Sven Jerrings Fond
- Swedish Research Council [2016-01009] Funding Source: Swedish Research Council
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The objective was to evaluate the effects of the Small Step Program on general development in children at risk of cerebral palsy (CP) or other neurodevelopmental disorders. A randomized controlled trial compared Small Step with Standard Care in infants recruited at 4-9 months of corrected age (CA). The 35-week intervention targeted mobility, hand use, and communication during distinct periods. The Peabody Developmental Motor Scales(2ed) (PDMS-2) was the primary outcome measure. For statistical analysis, a general linear model used PDMS-2 as the main outcome variable, together with a set of independent variables. Thirty-nine infants were randomized to Small Step (n = 19, age 6.3 months CA (1.62 SD)) or Standard Care (n = 20, age 6.7 months CA (1.96 SD)). Administering PDMS-2 at end of treatment identified no group effect, but an interaction between group and PDMS-2 at baseline was found (p < 0.02). Development was associated with baseline assessments in the Standard Care group, while infants in the Small Step group developed independent of the baseline level, implying that Small Step helped the most affected children to catch up by the end of treatment. This result was sustained at 2 years of age for PDMS-2 and the PEDI mobility scale.
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