4.8 Article

Structure of the saxiphilin: saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins

Huaizong Shen et al.

SCIENCE (2019)

Article Chemistry, Multidisciplinary

Divergent Synthesis of Natural Derivatives of (+)-Saxitoxin Including 11-Saxitoxinethanoic Acid

James R. Walker et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Applied

Receptor binding assay for the detection of paralytic shellfish poisoning toxins: comparison to the mouse bioassay and applicability under regulatory use

Shiyamalie R. Ruberu et al.

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT (2018)

Review Biochemistry & Molecular Biology

Self-Resistance of Natural Product Producers: Past, Present, and Future Focusing on Self-Resistant Protein Variants

Khaled H. Almabruk et al.

ACS CHEMICAL BIOLOGY (2018)

Article Multidisciplinary Sciences

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

Huaizong Shen et al.

SCIENCE (2018)

Review Chemistry, Medicinal

Guanidinium Toxins and Their Interactions with Voltage-Gated Sodium Ion Channels

Lorena M. Duran-Riveroll et al.

MARINE DRUGS (2017)

Article Multidisciplinary Sciences

K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site

Marco Lolicato et al.

NATURE (2017)

Article Multidisciplinary Sciences

Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance

Rebecca D. Tarvin et al.

SCIENCE (2017)

Article Biochemistry & Molecular Biology

Advances in high-resolution cryo-EM of oligomeric enzymes

Janet Vonck et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)

Article Multidisciplinary Sciences

Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7

Rhiannon Thomas-Tran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Biochemical Research Methods

EMRinger: side chain directed model and map validation for 3D cryo-electron microscopy

Benjamin A. Barad et al.

NATURE METHODS (2015)

Article Biochemical Research Methods

FEM: feature-enhanced map

Pavel V. Afonine et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2015)

Review Chemistry, Multidisciplinary

Saxitoxin

Arun P. Thottumkara et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Biochemical Research Methods

A robust pipeline for rapid production of versatile nanobody repertoires

Peter C. Fridy et al.

NATURE METHODS (2014)

Article Multidisciplinary Sciences

Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy

Alberto Bartesaghi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Crystal structure and its bearing towards an understanding of key biological functions of EpCAM

Miha Pavsic et al.

NATURE COMMUNICATIONS (2014)

Article Biochemical Research Methods

Model morphing and sequence assignment after molecular replacement

Thomas C. Terwilliger et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2013)

Article Biochemical Research Methods

How good are my data and what is the resolution?

Philip R. Evans et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2013)

Article Chemistry, Multidisciplinary

Maleimide Conjugates of Saxitoxin as Covalent Inhibitors of Voltage-Gated Sodium Channels

William H. Parsons et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Review Biochemistry & Molecular Biology

X-ray structures of transferrins and related proteins

Kimihiko Mizutani et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)

Review Biochemistry & Molecular Biology

Molecular evolution of the transferrin family and associated receptors

Lisa A. Lambert

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)

Article Multidisciplinary Sciences

The distribution of ligand-binding pockets around protein-protein interfaces suggests a general mechanism for pocket formation

Mu Gao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Chemistry, Applied

Paralytic shellfish poisoning (PSP) toxin binders for optical biosensor technology: problems and possibilities for the future: a review

K. Campbell et al.

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT (2011)

Article Multidisciplinary Sciences

Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins

David Shaya et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemical Research Methods

XDS

Wolfgang Kabsch

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Pharmacology & Pharmacy

Dynamics of saxitoxin binding to saxiphilin c-lobe reveals conformational change

Penny Lewis et al.

TOXICON (2008)

Article Multidisciplinary Sciences

Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins

Tomasz Sitar et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding

Jeremy Wally et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Diversity and evolution of the thyroglobulin type-1 domain superfamily

M Novinec et al.

MOLECULAR BIOLOGY AND EVOLUTION (2006)

Review Biochemistry & Molecular Biology

Saxitoxin, a toxic marine natural product that targets a multitude of receptors

LE Llewellyn

NATURAL PRODUCT REPORTS (2006)

Review Biochemistry & Molecular Biology

Evolution of the transferrin family: Conservation of residues associated with iron and anion binding

LA Lambert et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2005)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Pharmacology & Pharmacy

Saxitoxin blocks L-type/(Ca)

Z Su et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Article Instruments & Instrumentation

SOLVE and RESOLVE: automated structure solution, density modification, and model building

T Terwilliger

JOURNAL OF SYNCHROTRON RADIATION (2004)

Article Physiology

Saxitoxin is a gating modifier of hERG K+ channels

JX Wang et al.

JOURNAL OF GENERAL PHYSIOLOGY (2003)

Article Biochemical Research Methods

The crystal and molecular structures of diferric porcine and rabbit serum transferrins at resolutions of 2.15 and 2.60 angstrom, respectively

DR Hall et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2002)