Journal
JACC-HEART FAILURE
Volume 7, Issue 7, Pages 574-585Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jchf.2019.03.021
Keywords
heart failure; hemodynamics; pericardium
Categories
Funding
- U.S. National Institutes of Health [R01 HL128526, R01 HL 126638, U01 HL125205, U10 HL110262]
Ask authors/readers for more resources
The elastic pericardium exerts a compressive contact force on the surface of the myocardium that becomes more substantial when heart volume increases, as in patients with various forms of heart failure (HF). Pericardial restraint plays an important role in determining hemodynamics and ventricular function in both health and disease. This review discusses the physiology of pericardial restraint in HF and explores the question of whether it can be targeted indirectly through medical interventions or directly through a number of existing and future therapies. (C) 2019 by the American College of Cardiology Foundation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available