Journal
CLINICS IN COLON AND RECTAL SURGERY
Volume 32, Issue 4, Pages 305-313Publisher
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0039-1683923
Keywords
Crohn's disease; malignancy; cancer; inflammatory bowel disease
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Crohn's disease is associated with various intestinal and extraintestinal malignancies. This article reviews the current literature regarding Crohn's disease and subsequent risk of cancer formation. Recognition of risk factors (both modifiable and unmodifiable) is essential for prevention and appropriate screening. Future investigations into the molecular mechanisms associated with Crohn-related malignancy will provide additional insight into carcinogenesis, potential for early intervention, and identification of at-risk patients.
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