Journal
APPLIED SCIENCES-BASEL
Volume 9, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/app9112364
Keywords
aflatoxin B1; aptamer; detection
Categories
Funding
- National Natural Science Foundation of China [21705071, 21605074, 21805125]
- Natural Science Foundation of Guangdong province of China [2016A030310362, 2014A030310274, 2017A030310604, 2018A030313101]
- Lingnan Normal University [ZL1611]
- Research Group of Rare Earth Resource Exploiting and Luminescent Materials [2017KCXTD022]
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Aflatoxin B1 (AFB1) is one of the most frequently-found mycotoxins in contaminated food. As the content of mycotoxins is particularly low in food, the development of probes to detect AFB1 in foods with high sensitivity and selectivity is an urgent social need for the evaluation of food quality. Numerous techniques have been developed to monitor AFB1. Nevertheless, most of them require cumbersome, labor-consuming, and sophisticated instruments, which have limited their application. An aptamer is a single, short nucleic acid sequence that is capable of recognizing different targets. Owing to their unique properties, aptamers have been considered as alternatives to antibodies. Aptasensors are considered to be an emerging strategy for the quantification of aflatoxin B1 with high selectivity and sensitivity. In this review, we summarize recent developments in colormetric, electrochemical, SERS, and fluorescent aptasensors for the quantification of AFB1. Finally, the perspectives and current challenges of aptasensors for AFB1 are outlined.
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