4.5 Article

Near-ubiquitous presence of a vancomycin-resistant Enterococcus faecium ST117/CT71/vanB -clone in the Rhine-Main metropolitan area of Germany

Journal

Publisher

BMC
DOI: 10.1186/s13756-019-0573-8

Keywords

VRE; ST117; cgMLST; WGS

Funding

  1. Bundesministerium fuer Bildung und Forschung (BMBF, Germany) within the German Center for Infection research (DZIF/grant) [8032808811]
  2. Hessian Ministry of Social Affairs and Integration for the MDRO Network Rhine-Main
  3. Hessian Ministry of Higher Education, Research and Arts within the project HuKKH (Hessisches universitaeres Kompetenzzentrum Krankenhaushygiene)

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Whole-genome sequencing analysis of Vancomycin-resistant Enterococcus faecium isolates from the Frankfurt metropolitan region revealed that 78/94 isolates were MLST type ST117, cgMLST complex type CT71 with a common vanB chromosomal insertion site. This indicates circulation of a single VRE clone in a catchment area of 5,000-km(2) with 3 million inhabitants.

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