Journal
MICROMACHINES
Volume 10, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/mi10060422
Keywords
near-infrared fluorescence probes (NIFPs); immunochromatographic test strips (ICTSs); quantum dots; rare earth compounds; immunoassay; pathogen detection
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Funding
- National Key RAMP
- D Program of China, Ministry of Science and Technology of PR China [2018YFC1603804]
- Science and Technology Planning Project of General Administration of Customs of the People's Republic of China [2017IK157]
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Near-infrared fluorescence probes (NIFPs) have been widely used in immunoassay, bio-imaging and medical diagnosis. We review the basic principles of near-infrared fluorescence and near-infrared detection technology, and summarize structures, properties and characteristics of NIFPs (i.e., cyanines, xanthenes fluorescent dyes, phthalocyanines, porphyrin derivates, single-walled carbon nanotubes (SWCNTs), quantum dots and rare earth compounds). We next analyze applications of NIFPs in immunoassays, and prospect the application potential of lateral flow assay (LFA) in rapid detection of pathogens. At present, our team intends to establish a new platform that has highly sensitive NIFPs combined with portable and simple immunochromatographic test strips (ICTSs) for rapid detection of food-borne viruses. This will provide technical support for rapid detection on the port.
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