4.5 Article

Microwave-Assisted Ruthenium(II)-Catalyzed C-H/N-O Activation of N-Methoxybenzamides with Alkynylsulfane

Journal

ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 8, Issue 10, Pages 1830-1833

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.201900383

Keywords

C-H activation; ruthenium; alkynylsulfanes; 4-aryl-3-(aryl; alkylthio)isoquinolin-1(2H)-ones; microwave chemistry

Funding

  1. Ministry of Science and Technology ROC [MOST 107-2113-M-003-003]

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An annulation of phenyl(phenylethynyl)sulfane and N-methoxybenzamides through ruthenium C-H/N-O activation is reported. A wide variety of 4-aryl-3-(aryl/alkylthio)isoquinolin-1(2H)-one derivatives are obtained in moderate to good yields.

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