Ligand Free Heterogeneous Sonogashira Cross-Coupling Reaction over an in Situ Organoiodine Capsulized Palladium Anchored to a Perovskite Catalyst

An environmentally friendly Sonogashira cross-coupling reaction is described in this study with high potential for application in a fluidized system. The LaCo0.9Ni0.05Pd0.05O3 perovskite based catalyst provided a high turnover frequency (TOF) of 900 h(-1) via mainly a heterogeneous mechanism in an environmentally friendly mixed medium of water and acetonitrile. Nanosized Pd(0) sites were anchored to the surface of perovskite using an in situ formed colloidal agent. This capsulizing agent was found to consist of organic compounds containing iodine atoms that interacted strongly with basic sites of the hydrophobic perovskite carrier using adsorption forces. This study illustrates a unique and strong principle for designing green heterogeneous catalysts for common valuable organic reactions.