4.7 Article

Disease-linked mutations alter the stoichiometries of HCN-KCNE2 complexes

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Structures of the Human HCN1 Hyperpolarization-Activated Channel

Chia-Hsueh Lee et al.

Article Cardiac & Cardiovascular Systems

Ectopic automaticity induced in ventricular myocytes by transgenic overexpression of HCN2

Kensuke Oshita et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)

Article Multidisciplinary Sciences

Functional Characterization of Cnidarian HCN Channels Points to an Early Evolution of Ih

Emma C. Baker et al.

PLOS ONE (2015)

Article Cardiac & Cardiovascular Systems

A Novel HCN4 Mutation, G1097W, Is Associated With Atrioventricular Block

Jun Zhou et al.

CIRCULATION JOURNAL (2014)

Article Cardiac & Cardiovascular Systems

A novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation

Vincenzo Macri et al.

HEART RHYTHM (2014)

Article Cardiac & Cardiovascular Systems

HCN4 Mutations in Multiple Families With Bradycardia and Left Ventricular Noncompaction Cardiomyopathy

Annalisa Milano et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

Article Cardiac & Cardiovascular Systems

The Symptom Complex of Familial Sinus Node Dysfunction and Myocardial Noncompaction Is Associated With Mutations in the HCN4 Channel

Patrick A. Schweizer et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

Article Genetics & Heredity

De novo mutations in HCN1 cause early infantile epileptic encephalopathy

Caroline Nava et al.

NATURE GENETICS (2014)

Article Multidisciplinary Sciences

X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking

Anna Frick et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Cardiac & Cardiovascular Systems

Sick Sinus Syndrome in HCN1-Deficient Mice

Stefanie Fenske et al.

CIRCULATION (2013)

Article Cardiac & Cardiovascular Systems

An LQTS6 MiRP1 Mutation Suppresses Pacemaker Current and is Associated with Sinus Bradycardia

Pooja A. Nawathe et al.

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2013)

Article Multidisciplinary Sciences

Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

Haibo Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Cardiac & Cardiovascular Systems

Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts

Yoshihiro Kuwabara et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)

Review Biochemistry & Molecular Biology

KCNE2 and the K+ channel The tail wagging the dog

Geoffrey W. Abbott

CHANNELS (2012)

Article Biochemistry & Molecular Biology

Automating Single Subunit Counting of Membrane Proteins in Mammalian Cells

Hugo McGuire et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Cardiac & Cardiovascular Systems

Stoichiometry of the Slow Iks Potassium Channel in Human Embryonic Stem Cell-Derived Myocytes

Mi Wang et al.

PEDIATRIC CARDIOLOGY (2012)

Article Multidisciplinary Sciences

Targeted Deletion of Kcne2 Impairs HCN Channel Function in Mouse Thalamocortical Circuits

Shui-Wang Ying et al.

PLOS ONE (2012)

Review Biochemistry & Molecular Biology

Nano-environmental changes by KCNE proteins modify KCNQ channel function

Koichi Nakajo et al.

CHANNELS (2011)

Article Developmental Biology

Prefrontal cortical network connections: key site of vulnerability in stress and schizophrenia

Amy F. T. Arnsten

INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2011)

Article Multidisciplinary Sciences

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

Mirko Baruscotti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain

Edward C. Emery et al.

SCIENCE (2011)

Article Clinical Neurology

Augmented Currents of an HCN2 Variant in Patients with Febrile Seizure Syndromes

Leanne M. Dibbens et al.

ANNALS OF NEUROLOGY (2010)

Article Biochemistry & Molecular Biology

Dynamic changes in HCN2, HCN4, KCNE1, and KCNE2 expression in ventricular cells from acute myocardial infarction rat hearts

Shuang Xia et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Biochemistry & Molecular Biology

Confirmed rare copy number variants implicate novel genes in schizophrenia

Gloria W. C. Tam et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2010)

Article Biochemistry & Molecular Biology

Functional Delivery of a Membrane Protein into Oocyte Membranes Using Bicelles

Congbao Kang et al.

BIOCHEMISTRY (2010)

Article Cardiac & Cardiovascular Systems

cAMP Sensitivity of HCN Pacemaker Channels Determines Basal Heart Rate But Is Not Critical for Autonomic Rate Control

Patrick A. Schweizer et al.

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2010)

Article Clinical Neurology

Neonatal seizures and long QT Syndrome: A cardiocerebral channelopathy?

Sarah E. Heron et al.

EPILEPSIA (2010)

Article Cardiac & Cardiovascular Systems

KCNE2 modulation of Kv4.3 current and its potential role in fatal rhythm disorders

Jie Wu et al.

HEART RHYTHM (2010)

Article Cardiac & Cardiovascular Systems

A Novel Mutation in the HCN4 Gene Causes Symptomatic Sinus Bradycardia in Moroccan Jews

Avishag Laish-Farkash et al.

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2010)

Article Multidisciplinary Sciences

Stoichiometry of the KCNQ1-KCNE1 ion channel complex

Koichi Nakajo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Cardiac & Cardiovascular Systems

Effects of KCNE2 on HCN isoforms: distinct modulation of membrane expression and single channel properties

Mathias C. Brandt et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)

Article Genetics & Heredity

Role of HCN4 channel in preventing ventricular arrhythmia

Kazuo Ueda et al.

JOURNAL OF HUMAN GENETICS (2009)

Article Neurosciences

Loss of Dendritic HCN1 Subunits Enhances Cortical Excitability and Epileptogenesis

Zhuo Huang et al.

JOURNAL OF NEUROSCIENCE (2009)

Article Cardiac & Cardiovascular Systems

Molecular basis of funny current (If) in normal and failing human heart

Francesca Stillitano et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)

Article Biochemistry & Molecular Biology

HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice

Stefan Herrmann et al.

EMBO JOURNAL (2007)

Article Multidisciplinary Sciences

Differential Association between HERG and KCNE1 or KCNE2

Sung Yon Um et al.

PLOS ONE (2007)

Article Biochemistry & Molecular Biology

KCNE1 subunits require co-assembly with K+ channels for efficient trafficking and cell surface expression

Kshama D. Chandrasekhar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Neurosciences

Retinal bipolar cell types differ in their inventory of ion channels

Elena Ivanova et al.

VISUAL NEUROSCIENCE (2006)

Article Medicine, General & Internal

Brief report - Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel

R Milanesi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Biochemistry & Molecular Biology

Functional expression of the human HCN3 channel

J Stieber et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Cardiac & Cardiovascular Systems

Sudden infant death syndrome: How significant are the cardiac channelopathies?

DJ Tester et al.

CARDIOVASCULAR RESEARCH (2005)

Article Multidisciplinary Sciences

The channel architecture of aquaporin 0 at a 2.2-Å resolution

WEC Harries et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia

K Ueda et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

MiRP1 modulates HCN2 channel expression and gating in cardiac myocytes

JH Qu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

J Stieber et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Neurosciences

Cell type-dependent expression of HCN1 in the main olfactory bulb

NB Holderith et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2003)

Article Biochemistry & Molecular Biology

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

A Ludwig et al.

EMBO JOURNAL (2003)

Article Multidisciplinary Sciences

Visualization of a water-selective pore by electron crystallography in vitreous ice

G Ren et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Cardiac & Cardiovascular Systems

Myocardial remodeling and arrhythmogenesis in moderate cardiac hypertrophy in rats

D Stilli et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)

Article Biochemistry & Molecular Biology

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

N Tinel et al.

EMBO JOURNAL (2000)

Article Multidisciplinary Sciences

Structural determinants of water permeation through aquaporin-1

K Murata et al.

NATURE (2000)

Article Multidisciplinary Sciences

A common polymorphism associated with antibiotic-induced cardiac arrhythmia

F Sesti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Cardiac & Cardiovascular Systems

Spectrum of mutations in long-QT syndrome genes KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

I Splawski et al.

CIRCULATION (2000)

Article Biochemistry & Molecular Biology

M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit

N Tinel et al.

FEBS LETTERS (2000)