Journal
MATERIALS
Volume 12, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/ma12111874
Keywords
chitosan; chitin nanofibrils; composite matrix; tissue engineering
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Funding
- Russian Science Foundation [19-73-30003]
- Russian Science Foundation [19-73-30003] Funding Source: Russian Science Foundation
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This paper discusses the mechanical and physicochemical properties of film matrices based on chitosan, as well as the possibility of optimizing these properties by adding chitin nanofibrils. It is shown that with the introduction of chitin nanofibrils as a filler, the mechanical stability of the composite materials increases. By varying the concentration of chitin nanofibrils, it is possible to obtain a spectrum of samples with different bioactive properties for the growth of human dermal fibroblasts. Film matrices based on the nanocomposite of chitosan and 5 wt % chitin nanofibrils have an optimal balance of mechanical and physicochemical properties and bioactivity in relation to the culture of human dermal fibroblasts.
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