Journal
MATERIALS
Volume 12, Issue 13, Pages -Publisher
MDPI
DOI: 10.3390/ma12132107
Keywords
CALNN; peptide; gold nanoparticle; self-assembling; size; tyrosine; trypsin
Categories
Funding
- National Natural Science Foundation of China [21605074, 21705071]
- Natural Science Foundation of Guangdong Province [2014A030310274, 2016A030310362, 2017A030310604]
- Research Group of Rare Earth Resource Exploiting and Luminescent Materials [2017KCXTD022]
- Guangdong University Provincial Key Platform and Major Research Projects: Characteristic Innovation Project [2017KTSCX118]
- Natural Science Foundation of Lingnan Normal University [ZL1404, ZL1611]
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Gold nanoparticles (AuNPs) made from self-assembling peptides have been used in many research fields and attracted a great deal of attention due to their high stability, biocompatibility and functionality. However, existing preparation methods for peptide-coated AuNPs are post-synthesis processes, which are complicated and time consuming. Therefore, a one-step preparation method for peptide-coated AuNPs is proposed here. The AuNPs obtained by this method exhibit good stability. Importantly, peptide-coated AuNPs with precise different sizes can be prepared by this method through pH control of reducing reagent tyrosine in range of 10.0 similar to 12.7. Thus, the one-step preparation method proposed here provides a significant tool for the research in different fields concerning NP size, stability and biocompatibility.
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