Journal
BIOMEDICAL OPTICS EXPRESS
Volume 10, Issue 8, Pages 4220-4236Publisher
Optica Publishing Group
DOI: 10.1364/BOE.10.004220
Keywords
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Funding
- Russian Science Foundation (RSF) [17-75-10215, 18-15-00422]
- Russian Foundation for Basic Research (RFBR) [19-02-00947-a]
- Russian Science Foundation [17-75-10215, 18-15-00422] Funding Source: Russian Science Foundation
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Blood cell analysis is one of the standard clinical tests. Despite the widespread use of exogenous markers for blood cell quantification, label-free optical methods are still of high demand due to their possibility for in vivo application and signal specific to the biochemical state of the cell provided by native fluorophores. Here we report the results of blood cell characterization using label-free fluorescence imaging techniques and flow-cytometry. Autaluorescence parameters of different cell types white blood cells, red blood cells, erythrophagocytic cells are assessed and analyzed in terms of molecular heterogeneity and possibilities of differentiation between different cell types in vitro and in vivo. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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