4.8 Article

Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Senescence-associated reprogramming promotes cancer stemness

Maja Milanovic et al.

NATURE (2018)

Article Cell Biology

Regulation of senescence escape by the cdk4-EZH2-AP2M1 pathway in response to chemotherapy

Melanie Le Duff et al.

CELL DEATH & DISEASE (2018)

Review Biotechnology & Applied Microbiology

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

Avi Ashkenazi et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Review Biochemistry & Molecular Biology

Census and evaluation of p53 target genes

M. Fischer

ONCOGENE (2017)

Review Cell Biology

Poly(ADP-ribose) polymerase activity and inhibition in cancer

Caleb Dulaney et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2017)

Article

Oncogenic senescence: a multi-functional perspective

Darren J. Baker et al.

Oncotarget (2017)

Article Pharmacology & Pharmacy

PARP Inhibitors in Reproductive System Cancers: Current Use and Developments

Geraldine O'Sullivan Coyne et al.

DRUGS (2017)

Review Geriatrics & Gerontology

Premature aging/senescence in cancer cells facing therapy: good or bad?

Llilians Calvo Gonzalez et al.

BIOGERONTOLOGY (2016)

Article Biochemistry & Molecular Biology

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

Jianhui Chang et al.

NATURE MEDICINE (2016)

Review Geriatrics & Gerontology

Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype

Nicolas Malaquin et al.

EXPERIMENTAL GERONTOLOGY (2016)

Article Chemistry, Medicinal

An Update on Poly(ADP-ribose)polymerase-1 (PARP-1) Inhibitors: Opportunities and Challenges in Cancer Therapy

Ying-Qing Wang et al.

JOURNAL OF MEDICINAL CHEMISTRY (2016)

Article Medicine, General & Internal

Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer

M. R. Mirza et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Cell Biology

Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action

Yves Pommier et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

Reut Yosef et al.

NATURE COMMUNICATIONS (2016)

Review Chemistry, Medicinal

Deciphering the Insights of Poly(ADP-Ribosylation) in Tumor Progression

Maria Isabel Rodriguez et al.

MEDICINAL RESEARCH REVIEWS (2015)

Review Genetics & Heredity

DDR-mediated crosstalk between DNA-damaged cells and their microenvironment

Nicolas Malaquin et al.

FRONTIERS IN GENETICS (2015)

Review Medicine, General & Internal

The fate of chemoresistance in triple negative breast cancer (TNBC)

Elma A. O'Reilly et al.

BBA CLINICAL (2015)

Article Oncology

New Insights into PARP Inhibitors' Effect on Cell Cycle and Homology-Directed DNA Damage Repair

Petar Jelinic et al.

MOLECULAR CANCER THERAPEUTICS (2014)

Article Biotechnology & Applied Microbiology

A community computational challenge to predict the activity of pairs of compounds

Mukesh Bansal et al.

NATURE BIOTECHNOLOGY (2014)

Review Cell Biology

CHK2 kinase in the DNA damage response and beyond

Laura Zannini et al.

JOURNAL OF MOLECULAR CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning

Mekayla Storer et al.

Article Biochemistry & Molecular Biology

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

Jianjiong Gao et al.

SCIENCE SIGNALING (2013)

Article Medicine, General & Internal

Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer

Jonathan Ledermann et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Review Cell Biology

Four faces of cellular senescence

Francis Rodier et al.

JOURNAL OF CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

Integrated genomic analyses of ovarian carcinoma

D. Bell et al.

NATURE (2011)

Review Pathology

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

Jean -Philippe Coppe et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)

Article Multidisciplinary Sciences

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

Eric Campeau et al.

PLOS ONE (2009)

Article Biochemistry & Molecular Biology

Failure of stress-induced downregulation of Bcl-2 contributes to apoptosis resistance in senescent human diploid fibroblasts

S. J. Ryu et al.

CELL DEATH AND DIFFERENTIATION (2007)

Article Oncology

p53-independent regulation of p21Waf1/Cip1 expression and senescence by Chk2

CM Aliouat-Denis et al.

MOLECULAR CANCER RESEARCH (2005)

Article Biochemistry & Molecular Biology

Reversal of human cellular senescence:: roles of the p53 and p16 pathways

CM Beauséjour et al.

EMBO JOURNAL (2003)