Journal
TETRAHEDRON
Volume 75, Issue 30, Pages 3951-3957Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2019.05.057
Keywords
Fluorescent probe; Copper ion; Sulfide; Reversible; Bioimaging
Categories
Funding
- NSF of China [21572072]
- Science and Technology Innovation Program of the Universities of Henan Province [16HASTIT007]
- opening fund of Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medical [BCMM201801]
Ask authors/readers for more resources
A new coumarin-based fluorescent probe CMOH was easily synthesized for detection of Cu2+ and S2- in aqueous media and living cells. CMOH displayed high sensitivity (detection limit = 3.2 nM) and selectivity to Cu2+ with a non-fluorescence complex CMOH-Cu2+ formation via a 1:1 binding mode. According to displacement approach, the fluorescence of CMOH-Cu2+ was recovered in the presence of S2- and acted as a sensitive sensor with a low detection limit of 11.4 nM. This on-off-on process can be accomplished within 1 min and repeated at least 5 times. What's more, CMOH exhibited good permeability, low cytotoxicity and can be used as a suitable tool to detect changes of Cu2+ and S2- in biosystem. (C) 2019 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available