Related references
Note: Only part of the references are listed.Metals and Mechanisms of Carcinogenesis
Qiao Yi Chen et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 59 (2019)
The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors
Min He et al.
TRANSLATIONAL ONCOLOGY (2018)
COSMIC: somatic cancer genetics at high-resolution
Simon A. Forbes et al.
NUCLEIC ACIDS RESEARCH (2017)
Mutant KRAS Status Is Associated with Increased KRAS Copy Number Imbalance: a Potential Mechanism of Molecular Heterogeneity
Ott Docs et al.
PATHOLOGY & ONCOLOGY RESEARCH (2017)
Molecular insight of arsenic-induced carcinogenesis and its prevention
Paramita Mandal
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2017)
A comprehensive review of metal-induced cellular transformation studies
Qiao Yi Chen et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2017)
Mutant allele specific imbalance in oncogenes with copy number alterations: Occurrence, mechanisms, and potential clinical implications
Chih-Chieh Yu et al.
CANCER LETTERS (2017)
Not breathing is not an option: How to deal with oxidative DNA damage
Enni Markkanen
DNA REPAIR (2017)
Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks
Ryusuke Murakami et al.
AMERICAN JOURNAL OF PATHOLOGY (2017)
Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes
Robert M. Stephens et al.
CANCER INFORMATICS (2017)
KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer
Michael R. Burgess et al.
CELL (2017)
KrasG12D induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells
S. Diersch et al.
ONCOGENE (2016)
The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na+ channel (ENaC): IUPHAR Review 19
Emilie Boscardin et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Arsenic alters global histone modifications in lymphocytes in vitro and in vivo
Angeliki Pournara et al.
CELL BIOLOGY AND TOXICOLOGY (2016)
Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseases
Israel Hanukoglu et al.
GENE (2016)
Inorganic arsenic: A non-genotoxic carcinogen
Samuel M. Cohen et al.
JOURNAL OF ENVIRONMENTAL SCIENCES (2016)
The value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancers
Gajendra Shrestha et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2016)
KRAS Mutant Allele-Specific Imbalance (MASI) assessment in routine samples of patients with metastatic colorectal cancer
Umberto Malapelle et al.
JOURNAL OF CLINICAL PATHOLOGY (2015)
Epigenetic Targets of Arsenic: Emphasis on Epigenetic Modifications During Carcinogenesis
Ram Vinod Roy et al.
JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY (2015)
K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif
Frederick D. Tsai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Differential DNA methylation profile of key genes in malignant prostate epithelial cells transformed by inorganic arsenic or cadmium
Katherine E. Pelch et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2015)
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
Peter M. K. Westcott et al.
NATURE (2015)
Genotoxic and epigenetic mechanisms in arsenic carcinogenicity
Elisa Bustaffa et al.
ARCHIVES OF TOXICOLOGY (2014)
KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition
H. Hamidi et al.
BRITISH JOURNAL OF CANCER (2014)
Whole Genome Gene Copy Number Profiling of Gastric Cancer Identifies PAK1 and KRAS Gene Amplification as Therapy Targets
Ziliang Qian et al.
GENES CHROMOSOMES & CANCER (2014)
Silencing KRAS Overexpression in Arsenic-Transformed Prostate Epithelial and Stem Cells Partially Mitigates Malignant Phenotype
Ntube N. O. Ngalame et al.
TOXICOLOGICAL SCIENCES (2014)
Aberrant microRNA Expression Likely Controls RAS Oncogene Activation During Malignant Transformation of Human Prostate Epithelial and Stem Cells by Arsenic
Ntube N. O. Ngalame et al.
TOXICOLOGICAL SCIENCES (2014)
Basic mechanics of DNA methylation and the unique landscape of the DNA methylome in metal-induced carcinogenesis
Jason Brocato et al.
CRITICAL REVIEWS IN TOXICOLOGY (2013)
Clinicopathological correlates and prognostic significance of KRAS mutation status in a pooled prospective cohort of epithelial ovarian cancer
Bjorn Nodin et al.
DIAGNOSTIC PATHOLOGY (2013)
Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation
Paul L. Severson et al.
EPIGENETICS (2013)
KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy
Emanuele Valtorta et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
KRAS and MAPK1 Gene Amplification in Type II Ovarian Carcinomas
Mohammed Tanjimur Rahman et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
KRAS mutant allele-specific imbalance is associated with worse prognosis in pancreatic cancer and progression to undifferentiated carcinoma of the pancreas
Alyssa M. Krasinskas et al.
MODERN PATHOLOGY (2013)
K-ras 4A and 4B mRNA levels correlate with superoxide in lung adenocarcinoma cells, while at the protein level, only mutant K-ras 4A protein correlates with superoxide
Richard J. Calvert et al.
LUNG CANCER (2013)
RNA-Seq Profiling Reveals Novel Hepatic Gene Expression Pattern in Aflatoxin B1 Treated Rats
B. Alex Merrick et al.
PLOS ONE (2013)
Oxidative DNA damage after acute exposure to arsenite and monomethylarsonous acid in biomethylation-deficient human cells
Ruben Orihuela et al.
TOXICOLOGY MECHANISMS AND METHODS (2013)
Arsenic-Induced Genotoxicity and Genetic Susceptibility to Arsenic-Related Pathologies
Francesca Faita et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2013)
KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer
E. Birkeland et al.
BRITISH JOURNAL OF CANCER (2012)
Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation
Paul L. Severson et al.
EPIGENETICS (2012)
Mutant allele-specific imbalance modulates prognostic impact of KRAS mutations in colorectal adenocarcinoma and is associated with worse overall survival
D. J. Hartman et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Polycomb (PcG) Proteins, BMI1 and SUZ12, Regulate Arsenic-induced Cell Transformation
Hong-Gyum Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Combined point mutations in codon 12 and 13 of KRAS oncogene in prostate carcinomas
Fatma Silan et al.
MOLECULAR BIOLOGY REPORTS (2012)
Effects of Chronic Exposure to Arsenic and Estrogen on Epigenetic Regulatory Genes Expression and Epigenetic Code in Human Prostate Epithelial Cells
Justin N. Treas et al.
PLOS ONE (2012)
Identification of novel transcripts in annotated genomes using RNA-Seq
Adam Roberts et al.
BIOINFORMATICS (2011)
An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and Carcinogenesis
Xuefeng Ren et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2011)
KRAS mutant allele-specific imbalance in lung adenocarcinoma
Simion I. Chiosea et al.
MODERN PATHOLOGY (2011)
Genetic and epigenetic effects of environmental arsenicals
Toby G. Rossman et al.
METALLOMICS (2011)
Arsenic Exposure and Toxicology: A Historical Perspective
Michael F. Hughes et al.
TOXICOLOGICAL SCIENCES (2011)
Characterization of KRAS Rearrangements in Metastatic Prostate Cancer
Xiao-Song Wang et al.
CANCER DISCOVERY (2011)
Arsenic-Specific Stem Cell Selection During Malignant Transformation
Erik J. Tokar et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
Cole Trapnell et al.
NATURE BIOTECHNOLOGY (2010)
Effects of arsenic exposure on DNA methylation and epigenetic gene regulation
John F. Reichard et al.
EPIGENOMICS (2010)
Polarized fluid movement and not cell death, creates luminal spaces in adult prostate epithelium
J. F. Pearson et al.
CELL DEATH AND DIFFERENTIATION (2009)
Folate Deficiency, Hyperhomocysteinemia, Low Urinary Creatinine, and Hypomethylation of Leukocyte DNA Are Risk Factors for Arsenic-induced Skin Lesions
J. Richard Pilsner et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2009)
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: Nickel, arsenic, and chromium
Konstantin Salnikow et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
Inorganic arsenic and human prostate cancer
Lamia Benbrahim-Tallaa et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2008)
Does Arsenic Exposure Increase the Risk for Prostate Cancer?
Chun-Yuh Yang et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2008)
Kras regulatory elements and exon 4A determine mutation specificity in lung cancer
Minh D. To et al.
NATURE GENETICS (2008)
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
James A. McCubrey et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Insights into the carcinogenic mode of action of arsenic
A. D. Kligerman et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Further evidence against a direct genotoxic mode of action for arsenic-induced cancer
Catherine B. Klein et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
HER2, TOP2A, CCND1, EGFR and c-MYC oncogene amplification in colorectal cancer
Khawla Al-Kuraya et al.
JOURNAL OF CLINICAL PATHOLOGY (2007)
Mechanisms of acquired androgen independence during arsenic-induced malignant transformation of human prostate epithelial cells
Lamia Benbrahim-Tallaa et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2007)
Gene amplification in cancer
Donna G. Albertson
TRENDS IN GENETICS (2006)
Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells
Wanda H. Vila-Carriles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation
L Benbrahim-Tallaa et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)
Arsenic-induced enhancement of ultraviolet radiation carcinogenesis in mouse skin:: A dose-response study
FJ Burns et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2004)
Animal models for arsenic carcinogenesis: inorganic arsenic is a transplacental carcinogen in mice
MP Waalkes et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues: Implications for prostate carcinogenesis and progression of prostate cancer
ZG Zhao et al.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2004)
Arsenic toxicity, mutagenesis, and carcinogenesis a health risk assessment and management approach
PB Tchounwou et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2004)
Molecular mechanisms of arsenic carcinogenesis
CS Huang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2004)
Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells
OI Tchernitsa et al.
ONCOGENE (2004)
Inorganic arsenite-induced malignant transformation of human prostate epithelial cells
WE Achanzar et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2002)
Arsenic, drinking water, and health: A position paper of the American Council on Science and Health
KG Brown et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2002)
Arsenite cocarcinogenesis: An animal model derived from genetic toxicology studies
TG Rossman et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2002)
Chronic arsenic-exposed human prostate epithelial cells exhibit stable arsenic tolerance: Mechanistic implications of altered cellular glutathione and glutathione S-transferase
EM Brambila et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2002)
Wildtype Kras2 can inhibit lung carcinogenesis in mice
ZQ Zhang et al.
NATURE GENETICS (2001)
In vitro human cell culture models for the study of prostate cancer
JS Rhim
PROSTATE CANCER AND PROSTATIC DISEASES (2000)
Share Paper
