Journal
PHYTOTHERAPY RESEARCH
Volume 33, Issue 9, Pages 2152-2162Publisher
WILEY
DOI: 10.1002/ptr.6395
Keywords
arthritis; atherosclerosis; inflammatory bowel disease; neurodegenerative diseases; osteoporosis; type 1 diabetes
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Funding
- Italian Ministry of University Funding Source: Medline
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Devil's Claw is a traditional medicine that has been long used a wide range of health conditions, including indigestion, fever, allergic reactions, and rheumatism. The main compounds are iridoid glycosides, including harpagoside, harpagide, and procumbide. However, harpagoside is the most responsible for therapeutic activity, and its content is used as reference standard. Here, we analyzed and summarized preclinical and clinical studies focusing on therapeutic efficacy of devil's claw preparations in pathological conditions in which inflammation plays a key causative role.
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