4.3 Article

Four new triterpenoids from the bark of Euonymus alatus forma ciliato-dentatus

Journal

PHYTOCHEMISTRY LETTERS
Volume 31, Issue -, Pages 140-146

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2019.03.015

Keywords

Euonymus alatus forma ciliato-dentatus; Celastraceae; Triterpenoid; Lupane

Funding

  1. NIH [CA177584]
  2. National Cancer Institute

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Four novel lupane-type lupane-type triterpenoids (including three norlupane-type triterpenoids), 17 beta-hydroxy-28-norlup-20(29) en 3 one (1), 3 beta,17 beta-dihydroxy-28,30-bisnorlupan-20-one (2), 3 beta-hydroxy-20-oxo-30-norlupan-28-al (3) and lup-20(29)-ene-3,23,30-triol (4), were isolated together with ten known lupane triterpenoids (5(similar to)14) from the bark of Euonymus alatus forma ciliato-dentatus. Their structures were determined from 1D- and 2D-NMR analysis and comparison of their spectroscopic data with literature values. The known compounds (5(similar to)14) were reported for the first time from this plant.

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