Journal
PEDIATRIC BLOOD & CANCER
Volume 66, Issue 11, Pages -Publisher
WILEY
DOI: 10.1002/pbc.27917
Keywords
astrocytoma; bevacizumab; cyst; ganglioglioma; low-grade glioma; pediatric
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Low-grade gliomas (LGG) are among the most common types of brain tumors in children and young adults. These tumors often consist of solid and cystic components. Bevacizumab is a documented treatment for progressive LGG, yet the impact of therapy on the cystic component of these tumors is unknown. We present four patients with prominently cystic LGG treated with bevacizumab at the time of progression. In each case, the cystic component responded to treatment. This is the first known study to investigate bevacizumab's impact on the cystic component of low-grade gliomas.
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