Journal
ORGANIC LETTERS
Volume 21, Issue 15, Pages 6140-6144Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b02307
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Funding
- Pfizer
- H2020-FETOPEN-2016-2017 program of European commission [737266-ONE FLOW]
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Mild cross-coupling reaction between benzylboronic esters with carbonyl compounds and some imines was achieved under visible-light-induced iridium-catalyzed photoredox conditions. Functional group tolerance was demonstrated by 51 examples, including 13 heterocyclic compounds. Gram-scale reaction was realized through the use of computer-controlled continuous flow photoreactors.
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