Related references
Note: Only part of the references are listed.Mutant p53 as a guardian of the cancer cell
Fiamma Mantovani et al.
CELL DEATH AND DIFFERENTIATION (2019)
Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis
Eleonora Ingallina et al.
NATURE CELL BIOLOGY (2018)
Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others
Kanaga Sabapathy et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
Jianfang Liu et al.
CELL (2018)
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes
L. Montibeller et al.
CELL STRESS & CHAPERONES (2018)
The three branches of the unfolded protein response exhibit differential significance in breast cancer growth and sternness
Chuang Li et al.
EXPERIMENTAL CELL RESEARCH (2018)
Mutant p53 partners in crime
Michael P. Kim et al.
CELL DEATH AND DIFFERENTIATION (2018)
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer
Dawid Walerych et al.
NATURE CELL BIOLOGY (2016)
Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5
Fotini Vogiatzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Endoplasmic Reticulum Stress and the Hallmarks of Cancer
Hery Urra et al.
TRENDS IN CANCER (2016)
Adaptive Stress Responses During Tumor Metastasis and Dormancy
Daniela Senft et al.
TRENDS IN CANCER (2016)
Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis
Eric Chevet et al.
CANCER DISCOVERY (2015)
Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway
Takushi Namba et al.
ONCOTARGET (2015)
Nelfinavir and Nelfinavir Analogs Block Site-2 Protease Cleavage to Inhibit Castration-Resistant Prostate Cancer
Min Guan et al.
SCIENTIFIC REPORTS (2015)
Cell Surface GRP78 Accelerated Breast Cancer Cell Proliferation and Migration by Activating STAT3
Xiaoli Yao et al.
PLOS ONE (2015)
Endoplasmic Reticulum Stress in Malignancy
Hanna J. Clarke et al.
CANCER CELL (2014)
Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress
Kwang Hong Tay et al.
CELLULAR SIGNALLING (2014)
TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
Laxmi Silwal-Pandit et al.
CLINICAL CANCER RESEARCH (2014)
Mutant p53 Reprograms TNF Signaling in Cancer Cells through Interaction with the Tumor Suppressor DAB2IP
Giulio Di Minin et al.
MOLECULAR CELL (2014)
Phosphoregulation of Ire1 RNase splicing activity
Filippo Prischi et al.
NATURE COMMUNICATIONS (2014)
The impact of the endoplasmic reticulum protein-folding environment on cancer development
Miao Wang et al.
NATURE REVIEWS CANCER (2014)
Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer
Tomer Cooks et al.
CANCER CELL (2013)
Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress-Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis
Daniel A. Cunha et al.
DIABETES (2012)
SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis
D. Li et al.
CELL DEATH AND DIFFERENTIATION (2011)
Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6
Min Guan et al.
CLINICAL CANCER RESEARCH (2011)
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
Peter Walter et al.
SCIENCE (2011)
Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47
Karima Bourougaa et al.
MOLECULAR CELL (2010)
ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum
Yusuke Adachi et al.
CELL STRUCTURE AND FUNCTION (2008)
ATF6α-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo
Denis M. Schewe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ATF6α optimizes long-term endoplasmic reticulum function to protect cells from chronic stress
Jun Wu et al.
DEVELOPMENTAL CELL (2007)
ER stress triggers apoptosis by activating BH3-only protein Bim
Hamsa Puthalakath et al.
CELL (2007)
Autophagy is activated for cell survival after endoplasmic reticulum stress
Maiko Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
Ting-Chao Chou
PHARMACOLOGICAL REVIEWS (2006)
Roles of CHOP/GADD153 in endoplasmic reticulum stress
S Oyadomari et al.
CELL DEATH AND DIFFERENTIATION (2004)
ATF6 modulates SREBP2-mediated lipogenesis
LF Zeng et al.
EMBO JOURNAL (2004)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
H Yoshida et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)