Related references
Note: Only part of the references are listed.Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2
Christine R. Beck et al.
CELL (2019)
Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements
Lin Deng et al.
MOLECULAR CELL (2019)
Dynamic Processing of Displacement Loops during Recombinational DNA Repair
Aurae Piazza et al.
MOLECULAR CELL (2019)
TRAIP is a master regulator of DNA interstrand crosslink repair
R. Alex Wu et al.
NATURE (2019)
A Snapshot on the Cis Chromatin Response to DNA Double-Strand Breaks
Thomas Clouaire et al.
TRENDS IN GENETICS (2019)
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks
Gabriel Balmus et al.
NATURE COMMUNICATIONS (2019)
Factors affecting template switch recombination associated with restarted DNA replication
Manisha Jalan et al.
ELIFE (2019)
Nonhomologous DNA end-joining for repair of DNA double-strand breaks
Nicholas R. Pannunzio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta et al.
CELL (2018)
Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements
Carlos Mendez-Dorantes et al.
GENES & DEVELOPMENT (2018)
Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
Jeongkyu Kim et al.
MOLECULAR CELL (2018)
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
Harveer Dev et al.
NATURE CELL BIOLOGY (2018)
RPA and RAD51: fork reversal, fork protection, and genome stability
Kamakoti P. Bhat et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
RPA and RAD51: fork reversal, fork protection, and genome stability
Kamakoti P. Bhat et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading
Ravindra Amunugama et al.
CELL REPORTS (2018)
Rad51 recruitment and exclusion of non-homologous end joining during homologous recombination at a Tus/Ter mammalian replication fork barrier
Nicholas A. Willis et al.
PLOS GENETICS (2018)
Lesion Bypass and the Reactivation of Stalled Replication Forks
Kenneth J. Marians
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87 (2018)
Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse
Anthony Tubbs et al.
CELL (2018)
Preserving replication fork integrity and competence via the homologous recombination pathway
Anissia Ait Saada et al.
DNA REPAIR (2018)
FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange
Anaid Benitez et al.
MOLECULAR CELL (2018)
53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ
Hind Ghezraoui et al.
NATURE (2018)
The shieldin complex mediates 53BP1-dependent DNA repair
Sylvie M. Noordermeer et al.
NATURE (2018)
53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in
Zachary Mirman et al.
NATURE (2018)
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
Joseph Nacson et al.
CELL REPORTS (2018)
Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition
Nishita Shastri et al.
MOLECULAR CELL (2018)
Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks
Yang Yu et al.
NATURE (2018)
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells
Yizhou Joseph He et al.
NATURE (2018)
Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles
Weibin Wang et al.
GENES & DEVELOPMENT (2017)
Physiological protein blocks direct the Mre11-Rad50-Xrs2 and Sae2 nuclease complex to initiate DNA end resection
Giordano Reginato et al.
GENES & DEVELOPMENT (2017)
Homology Requirements and Competition between Gene Conversion and Break-Induced Replication during Double-Strand Break Repair
Anuja Mehta et al.
MOLECULAR CELL (2017)
Replication Fork Reversal: Players and Guardians
Annabel Quinet et al.
MOLECULAR CELL (2017)
Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity
Marko Vujanovic et al.
MOLECULAR CELL (2017)
Restoration of Replication Fork Stability in BRCA1-and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
Angelo Taglialatela et al.
MOLECULAR CELL (2017)
RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
Huzefa Dungrawala et al.
MOLECULAR CELL (2017)
Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments
Arun Mouli Kolinjivadi et al.
MOLECULAR CELL (2017)
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
Andrew N. Blackford et al.
MOLECULAR CELL (2017)
Mechanism of tandem duplication formation in BRCA1-mutant cells
Nicholas A. Willis et al.
NATURE (2017)
BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing
Weixing Zhao et al.
NATURE (2017)
Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
Nausica Arnoult et al.
NATURE (2017)
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function
Pascal Drane et al.
NATURE (2017)
Non-homologous DNA end joining and alternative pathways to double-strand break repair
Howard H. Y. Chang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
The helicase domain of Polθ counteracts RPA to promote alt-NHEJ
Pedro A. Mateos-Gomez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
PARP inhibitors: Synthetic lethality in the clinic
Christopher J. Lord et al.
SCIENCE (2017)
A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis
Markus Loebrich et al.
TRENDS IN BIOCHEMICAL SCIENCES (2017)
Nuclear Dynamics of Heterochromatin Repair
Nuno Amaral et al.
TRENDS IN GENETICS (2017)
Rad52 competes with Ku70/ Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination
Hong Zan et al.
NATURE COMMUNICATIONS (2017)
Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2
Rajula Elango et al.
NATURE COMMUNICATIONS (2017)
The helicase domain of Polθ counteracts RPA to promote alt-NHEJ
Pedro A. Mateos-Gomez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP
James M. Daley et al.
CELL REPORTS (2017)
Multi-invasions Are Recombination Byproducts that Induce Chromosomal Rearrangements
Aurele Piazza et al.
CELL (2017)
Chromatin organization and dynamics in double-strand break repair
Andrew Seeber et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2017)
A Life Investigating Pathways That Repair Broken Chromosomes
James E. Haber
ANNUAL REVIEW OF GENETICS, VOL 50 (2016)
Eukaryotic DNA Polymerases in Homologous Recombination
Mitch McVey et al.
ANNUAL REVIEW OF GENETICS, VOL 50 (2016)
Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase
Daniel R. Semlow et al.
CELL (2016)
The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress
Wojciech Piwko et al.
EMBO JOURNAL (2016)
Sgs1 and Mph1 Helicases Enforce the Recombination Execution Checkpoint During DNA Double-Strand Break Repair in Saccharomyces cerevisiae
Suvi Jain et al.
GENETICS (2016)
Ewing Tumor-associated Antigen 1 Interacts with Replication Protein A to Promote Restart of Stalled Replication Forks
Sumin Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Two-Stage Synapsis of DNA Ends during Non-homologous End Joining
Thomas G. W. Graham et al.
MOLECULAR CELL (2016)
The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation
Karine Jacquet et al.
MOLECULAR CELL (2016)
Temporal and Spatial Uncoupling of DNA Double Strand Break Repair Pathways within Mammalian Heterochromatin
Katerina Tsouroula et al.
MOLECULAR CELL (2016)
HELB Is a Feedback Inhibitor of DNA End Resection
Jan Tkac et al.
MOLECULAR CELL (2016)
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks
David W. Wyatt et al.
MOLECULAR CELL (2016)
RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress
Rahul Bhowmick et al.
MOLECULAR CELL (2016)
Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks
Sotirios K. Sotiriou et al.
MOLECULAR CELL (2016)
Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection
Roopesh Anand et al.
MOLECULAR CELL (2016)
Break-induced telomere synthesis underlies alternative telomere maintenance
Robert L. Dilley et al.
NATURE (2016)
H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex
Giulia Saredi et al.
NATURE (2016)
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Serena Nik-Zainal et al.
NATURE (2016)
ETAA1 acts at stalled replication forks to maintain genome integrity
Thomas E. Bass et al.
NATURE CELL BIOLOGY (2016)
Activation of the ATR kinase by the RPA-binding protein ETAA1
Peter Haahr et al.
NATURE CELL BIOLOGY (2016)
Transcription-replication conflicts: how they occur and how they are resolved
Tatiana Garcia-Muse et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
The Fanconi anaemia pathway: newyplayers and new functions
Raphael Ceccaldi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection
Ruth M. Densham et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Replication stress: getting back on track
Matteo Berti et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks
Lianne E. M. Vriend et al.
NUCLEIC ACIDS RESEARCH (2016)
PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line
Vipul Kumar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The tandem duplicator phenotype as a distinct genomic configuration in cancer
Francesca Menghi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins
Gabrielle J. Grundy et al.
NATURE COMMUNICATIONS (2016)
Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
Pauline Chanut et al.
NATURE COMMUNICATIONS (2016)
Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection
Ruth M. Densham et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Replication stress: getting back on track
Matteo Berti et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks
Josee Guirouilh-Barbat et al.
PLOS GENETICS (2016)
Sgs1 and Mph1 Helicases Enforce the Recombination Execution Checkpoint During DNA Double-Strand Break Repair in Saccharomyces cerevisiae
Suvi Jain et al.
GENETICS (2016)
53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair
Francisca Lottersberger et al.
CELL (2015)
What is the DNA repair defect underlying Fanconi anemia?
Julien P. Duxin et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
CtIP: A DNA damage response protein at the intersection of DNA metabolism
Nodar Makharashvili et al.
DNA REPAIR (2015)
Functions and regulation of the multitasking FANCM family of DNA motor proteins
Xiaoyu Xue et al.
GENES & DEVELOPMENT (2015)
Unifying the DNA End-processing Roles of the Artemis Nuclease KU-DEPENDENT ARTEMIS RESECTION AT BLUNT DNA ENDS
Howard H. Y. Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
Ralph Zellweger et al.
JOURNAL OF CELL BIOLOGY (2015)
Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements
Cynthia J. Sakofsky et al.
MOLECULAR CELL (2015)
Differential Phosphorylation of DNA-PKcs Regulates the Interplay between End-Processing and End-Ligation during Nonhomologous End-Joining
Wenxia Jiang et al.
MOLECULAR CELL (2015)
A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination
Anderson T. Wang et al.
MOLECULAR CELL (2015)
BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair
Elodie Hatchi et al.
MOLECULAR CELL (2015)
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
Vera Boersma et al.
NATURE (2015)
Replication stress activates DNA repair synthesis in mitosis
Sheroy Minocherhomji et al.
NATURE (2015)
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
Raphael Ceccaldi et al.
NATURE (2015)
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination
Pedro A. Mateos-Gomez et al.
NATURE (2015)
A mechanism for the suppression of homologous recombination in G1 cells
Alexandre Orthwein et al.
NATURE (2015)
REV7 counteracts DNA double-strand break resection and affects PARP inhibition
Guotai Xu et al.
NATURE (2015)
Replication fork reversal in eukaryotes: from dead end to dynamic response
Kai J. Neelsen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
DNA interstrand cross-link repair requires replication-fork convergence
Jieqiong Zhang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Mus81 and converging forks limit the mutagenicity of replication fork breakage
Ryan Mayle et al.
SCIENCE (2015)
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
Takashi Ochi et al.
SCIENCE (2015)
Regulation of Recombination and Genomic Maintenance
Wolf-Dietrich Heyer
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins
Rohit Prakash et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair
Xue-Song Liu et al.
NATURE COMMUNICATIONS (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
DNA interstrand cross-link repair requires replication-fork convergence
Jieqiong Zhang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse
Michael O. Nguyen et al.
ELIFE (2015)
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
Richard L. Frock et al.
NATURE BIOTECHNOLOGY (2015)
Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement
Nicholas A. Willis et al.
TRENDS IN CANCER (2015)
Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis
Nam Woo Cho et al.
CELL (2014)
Genome-wide analysis reveals a role for BRCA1 and PALB2 in transcriptional co-activation
Alessandro Gardini et al.
EMBO JOURNAL (2014)
Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage
Sarah J. Hill et al.
GENES & DEVELOPMENT (2014)
Template Switching During Break-Induced Replication Is Promoted by the Mph1 Helicase in Saccharomyces cerevisiae
Anamarija Stafa et al.
GENETICS (2014)
Polymerase theta-mediated end joining of replication-associated DNA breaks in C.elegans
Sophie F. Roerink et al.
GENOME RESEARCH (2014)
CtIP-mediated resection is essential for viability and can operate independently of BRCA1
Federica Polato et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
XPF-ERCC1 Acts in Unhooking DNA Interstrand Crosslinks in Cooperation with FANCD2 and FANCP/SLX4
Daisy Klein Douwel et al.
MOLECULAR CELL (2014)
Dephosphorylation Enables the Recruitment of 53BP1 to Double-Strand DNA Breaks
Dong-Hyun Lee et al.
MOLECULAR CELL (2014)
BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks
Nicholas A. Willis et al.
NATURE (2014)
Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks
Elda Cannavo et al.
NATURE (2014)
Causes and consequences of replication stress
Michelle K. Zeman et al.
NATURE CELL BIOLOGY (2014)
Visualization of recombination-mediated damage bypass by template switching
Michele Giannattasio et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
Francois Aymard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Quantitation of DNA double-strand break resection intermediates in human cells
Yi Zhou et al.
NUCLEIC ACIDS RESEARCH (2014)
Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells
Lorenzo Costantino et al.
SCIENCE (2014)
Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions
Alexandre Orthwein et al.
SCIENCE (2014)
53BP1: pro choice in DNA repair
Michal Zimmerman et al.
TRENDS IN CELL BIOLOGY (2014)
The Dissolution of Double Holliday Junctions
Anna H. Bizard et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites
Wouter Koole et al.
NATURE COMMUNICATIONS (2014)
Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice
Nozomi Tomimatsu et al.
NATURE COMMUNICATIONS (2014)
BRCA1 Accelerates CtIP-Mediated DNA-End Resection
Andres Cruz-Garcia et al.
CELL REPORTS (2014)
Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ
Matthew J. Yousefzadeh et al.
PLOS GENETICS (2014)
53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions
Elsa Callen et al.
CELL (2013)
Chromatin Remodeling at DNA Double-Strand Breaks
Brendan D. Price et al.
CELL (2013)
APLF promotes the assembly and activity of non-homologous end joining protein complexes
Gabrielle J. Grundy et al.
EMBO JOURNAL (2013)
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
Cheng-Zhong Zhang et al.
GENES & DEVELOPMENT (2013)
A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
Sebastien Britton et al.
JOURNAL OF CELL BIOLOGY (2013)
Replication Stress-Induced Genome Instability: The Dark Side of Replication Maintenance by Homologous Recombination
Antony M. Carr et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
The DNA Translocase FANCM/MHF Promotes Replication Traverse of DNA Interstrand Crosslinks
Jing Huang et al.
MOLECULAR CELL (2013)
RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
J. Ross Chapman et al.
MOLECULAR CELL (2013)
A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
Cristina Escribano-Diaz et al.
MOLECULAR CELL (2013)
Regulation of DNA Damage Responses by Ubiquitin and SUMO
Stephen P. Jackson et al.
MOLECULAR CELL (2013)
Double strand break repair functions of histone H2AX
Ralph Scully et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2013)
Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration
Marenda A. Wilson et al.
NATURE (2013)
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
Amelie Fradet-Turcotte et al.
NATURE (2013)
Migrating bubble during break-induced replication drives conservative DNA synthesis
Natalie Saini et al.
NATURE (2013)
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
Jiangbo Tang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
53BP1 Regulates DSB Repair Using Rif1 to Control 5′ End Resection
Michal Zimmermann et al.
SCIENCE (2013)
Spatial Dynamics of Chromosome Translocations in Living Cells
Vassilis Roukos et al.
SCIENCE (2013)
Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching
Michela Di Virgilio et al.
SCIENCE (2013)
Break-Induced DNA Replication
Ranjith P. Anand et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids
Gurushankar Chandramouly et al.
NATURE COMMUNICATIONS (2013)
The Ku Heterodimer and the Metabolism of Single-Ended DNA Double-Strand Breaks
Alessia Balestrini et al.
CELL REPORTS (2013)
Coincident Resection at Both Ends of Random, γ-Induced Double-Strand Breaks Requires MRX (MRN), Sae2 (Ctp1), and Mre11-Nuclease
James W. Westmoreland et al.
PLOS GENETICS (2013)
A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2
Katharina Schlacher et al.
CANCER CELL (2012)
Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations
Yu Zhang et al.
CELL (2012)
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
J. Ross Chapman et al.
JOURNAL OF CELL SCIENCE (2012)
Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI
George-Lucian Moldovan et al.
MOLECULAR CELL (2012)
Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions
Steven A. Roberts et al.
MOLECULAR CELL (2012)
LEDGF (p75) promotes DNA-end resection and homologous recombination
Mads Daugaard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Competition between Replicative and Translesion Polymerases during Homologous Recombination Repair in Drosophila
Daniel P. Kanel et al.
PLOS GENETICS (2012)
Double-Strand Break End Resection and Repair Pathway Choice
Lorraine S. Symington et al.
ANNUAL REVIEW OF GENETICS, VOL 45 (2011)
Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
Katharina Schlacher et al.
CELL (2011)
Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair
Irene Chiolo et al.
CELL (2011)
Factors determining DNA double-strand break repair pathway choice in G2 phase
Atsushi Shibata et al.
EMBO JOURNAL (2011)
Destroying the ring: Freeing DNA from Ku with ubiquitin
Lisa Postow
FEBS LETTERS (2011)
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
Amitabh V. Nimonkar et al.
GENES & DEVELOPMENT (2011)
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
Yiduo Hu et al.
GENES & DEVELOPMENT (2011)
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
Sophie E. Polo et al.
GENES & DEVELOPMENT (2011)
The BRCA1-RAP80 Complex Regulates DNA Repair Mechanism Utilization by Restricting End Resection
Kara A. Coleman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage
Steven S. Foster et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
PARP-3 and APLF Function Together to Accelerate Nonhomologous End-Joining
Stuart L. Rulten et al.
MOLECULAR CELL (2011)
Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination
Kyosuke Nakamura et al.
MOLECULAR CELL (2011)
Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
Lilach Moyal et al.
MOLECULAR CELL (2011)
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes
Beth A. Helmink et al.
NATURE (2011)
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks
Shan Zha et al.
NATURE (2011)
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
Valerie Garcia et al.
NATURE (2011)
Rad51 paralogues Rad55-Rad57 balance the antirecombinase Srs2 in Rad51 filament formation
Jie Liu et al.
NATURE (2011)
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
Jiri Lukas et al.
NATURE CELL BIOLOGY (2011)
Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication
Koji Nakanishi et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair
David T. Long et al.
SCIENCE (2011)
Break-Induced Replication Is Highly Inaccurate
Angela Deem et al.
PLOS BIOLOGY (2011)
Regulation of Homologous Recombination in Eukaryotes
Wolf-Dietrich Heyer et al.
ANNUAL REVIEW OF GENETICS, VOL 44 (2010)
53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
Samuel F. Bunting et al.
CELL (2010)
The FANCM family of DNA helicases/translocases
Matthew C. Whitby
DNA REPAIR (2010)
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells
Wojciech Piwko et al.
EMBO JOURNAL (2010)
Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2
Eleni P. Mimitou et al.
EMBO JOURNAL (2010)
DNA damage signaling in response to double-strand breaks during mitosis
Simona Giunta et al.
JOURNAL OF CELL BIOLOGY (2010)
The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination
Lara O'Donnell et al.
MOLECULAR CELL (2010)
Identification of the MMS22L-TONSL Complex that Promotes Homologous Recombination
Eris Duro et al.
MOLECULAR CELL (2010)
Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange
Sarah Lambert et al.
MOLECULAR CELL (2010)
Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair
Eva Petermann et al.
MOLECULAR CELL (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
Purified human BRCA2 stimulates RAD51-mediated recombination
Ryan B. Jensen et al.
NATURE (2010)
Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation
Deniz Simsek et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA
Tina Thorslund et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
Peter Bouwman et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
Amy Marie et al.
NUCLEIC ACIDS RESEARCH (2010)
Increased Mutagenesis and Unique Mutation Signature Associated with Mitotic Gene Conversion
Wade M. Hicks et al.
SCIENCE (2010)
Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila
Sze Ham Chan et al.
PLOS GENETICS (2010)
Mechanisms of double-strand break repair in somatic mammalian cells
Andrea J. Hartlerode et al.
BIOCHEMICAL JOURNAL (2009)
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
Carsten Doil et al.
CELL (2009)
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
Grant S. Stewart et al.
CELL (2009)
MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks
Genze Shao et al.
GENES & DEVELOPMENT (2009)
MERIT40 facilitates BRCA1 localization and DNA damage repair
Lin Feng et al.
GENES & DEVELOPMENT (2009)
A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair
Suvi Jain et al.
GENES & DEVELOPMENT (2009)
RecQ helicases: multiple structures for multiple functions?
Alessandro Vindigni et al.
HFSP JOURNAL (2009)
The ubiquitin landscape at DNA double-strand breaks
Troy E. Messick et al.
JOURNAL OF CELL BIOLOGY (2009)
XRCC2 and XRCC3 Regulate the Balance between Short- and Long-Tract Gene Conversions between Sister Chromatids
Ganesh Nagaraju et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
A Selective Requirement for 53BP1 in the Biological Response to Genomic Instability Induced by Brca1 Deficiency
Liu Cao et al.
MOLECULAR CELL (2009)
Multiple functions of MRN in end-joining pathways during isotype class switching
Maria Dinkelmann et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
Anyong Xie et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair
Puck Knipscheer et al.
SCIENCE (2009)
A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation
P. J. Hastings et al.
PLOS GENETICS (2009)
Mechanism of eukaryotic homologous recombination
Joseph San Filippo et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination
Louise J. Barber et al.
CELL (2008)
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair
R. Scott Williams et al.
CELL (2008)
Mechanism of replication-coupled DNA interstrand crosslink repair
Markus Raeschle et al.
CELL (2008)
Break-induced replication - What is it and what is it for?
Bertrand Llorente et al.
CELL CYCLE (2008)
APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation
Chloe J. Macrae et al.
DNA REPAIR (2008)
Homologous recombination in real time: DNA strand exchange by RecA
Thijn van der Heijden et al.
MOLECULAR CELL (2008)
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
Aaron A. Goodarzi et al.
MOLECULAR CELL (2008)
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Eleni P. Mimitou et al.
NATURE (2008)
CDK targets Sae2 to control DNA-end resection and homologous recombination
Pablo Huertas et al.
NATURE (2008)
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
Nadya Dimitrova et al.
NATURE (2008)
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
Zhucheng Chen et al.
NATURE (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms
Celia Payen et al.
PLOS GENETICS (2008)
Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair
Nicole Bennardo et al.
PLOS GENETICS (2008)
A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
Jennifer A. Lee et al.
CELL (2007)
Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair
Anyong Xie et al.
MOLECULAR CELL (2007)
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
Bettina M. Lengsfeld et al.
MOLECULAR CELL (2007)
Human CtIP promotes DNA end resection
Alessandro A. Sartori et al.
NATURE (2007)
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
Oliver Limbo et al.
MOLECULAR CELL (2007)
IgH class switching and translocations use a robust non-classical end-joining pathway
Catherine T. Yan et al.
NATURE (2007)
Break-induced replication and telomerase-independent telomere maintenance require Pol32
John R. Lydeard et al.
NATURE (2007)
Positional stability of single double-strand breaks in mammalian cells
Evi Soutoglou et al.
NATURE CELL BIOLOGY (2007)
Template switching during break-induced replication
Catherine E. Smith et al.
NATURE (2007)
Replisome assembly and the direct restart of stalled replication forks
Ryan C. Heller et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C
Ganesh Nagaraju et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Mechanism of homologous recombination: mediators and helicases take on regulatory functions
Patrick Sung et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks
Kyoko Nakamura et al.
DNA REPAIR (2006)
γH2AX and MDC1:: Anchoring the DNA-damage-response machinery to broken chromosomes
M Stucki et al.
DNA REPAIR (2006)
On the mechanism of gene amplification induced under stress in Escherichia coli
Andrew Slack et al.
PLOS GENETICS (2006)
The RecA binding locus of RecBCD is a general domain for recruitment of DNA strand exchange proteins
M Spies et al.
MOLECULAR CELL (2006)
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
P Ahnesorg et al.
CELL (2006)
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
D Buck et al.
CELL (2006)
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
M Lopes et al.
MOLECULAR CELL (2006)
Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier
S Lambert et al.
CELL (2005)
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
JH Lee et al.
SCIENCE (2005)
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
HJ Yang et al.
NATURE (2005)
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
JH Lee et al.
SCIENCE (2004)
Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains
JA Aten et al.
SCIENCE (2004)
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
Y Aylon et al.
EMBO JOURNAL (2004)
The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm
N Shima et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
XC Yu et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Genetic steps of mammalian homologous repair with distinct mutagenic consequences
JM Stark et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila
M McVey et al.
GENETICS (2004)
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
G Ira et al.
NATURE (2004)
In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination
N Sugawara et al.
MOLECULAR CELL (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
DNA helicase Srs2 disrupts the Rad51 presynaptic filament
L Krejci et al.
NATURE (2003)
An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication
V Costanzo et al.
MOLECULAR CELL (2003)
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
LS Symington
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2002)
Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
M Frank-Vaillant et al.
MOLECULAR CELL (2002)
Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences
G Ira et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
JM Sogo et al.
SCIENCE (2002)
Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III
T Caspari et al.
GENES & DEVELOPMENT (2002)
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
AJ Pierce et al.
GENES & DEVELOPMENT (2001)
ATR and ATRIP: Partners in checkpoint signaling
D Cortez et al.
SCIENCE (2001)
The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations
DO Ferguson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Ku recruits the XRCC4-ligase IV complex to DNA ends
SAN McElhinny et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Share Paper
