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ANNUAL REVIEW OF GENETICS, VOL 44 (2010)
53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
Samuel F. Bunting et al.
CELL (2010)
The FANCM family of DNA helicases/translocases
Matthew C. Whitby
DNA REPAIR (2010)
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells
Wojciech Piwko et al.
EMBO JOURNAL (2010)
Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2
Eleni P. Mimitou et al.
EMBO JOURNAL (2010)
DNA damage signaling in response to double-strand breaks during mitosis
Simona Giunta et al.
JOURNAL OF CELL BIOLOGY (2010)
The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination
Lara O'Donnell et al.
MOLECULAR CELL (2010)
Identification of the MMS22L-TONSL Complex that Promotes Homologous Recombination
Eris Duro et al.
MOLECULAR CELL (2010)
Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange
Sarah Lambert et al.
MOLECULAR CELL (2010)
Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair
Eva Petermann et al.
MOLECULAR CELL (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
Purified human BRCA2 stimulates RAD51-mediated recombination
Ryan B. Jensen et al.
NATURE (2010)
Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation
Deniz Simsek et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA
Tina Thorslund et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
Peter Bouwman et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
Amy Marie et al.
NUCLEIC ACIDS RESEARCH (2010)
Increased Mutagenesis and Unique Mutation Signature Associated with Mitotic Gene Conversion
Wade M. Hicks et al.
SCIENCE (2010)
Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila
Sze Ham Chan et al.
PLOS GENETICS (2010)
Mechanisms of double-strand break repair in somatic mammalian cells
Andrea J. Hartlerode et al.
BIOCHEMICAL JOURNAL (2009)
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
Carsten Doil et al.
CELL (2009)
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
Grant S. Stewart et al.
CELL (2009)
MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks
Genze Shao et al.
GENES & DEVELOPMENT (2009)
MERIT40 facilitates BRCA1 localization and DNA damage repair
Lin Feng et al.
GENES & DEVELOPMENT (2009)
A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair
Suvi Jain et al.
GENES & DEVELOPMENT (2009)
RecQ helicases: multiple structures for multiple functions?
Alessandro Vindigni et al.
HFSP JOURNAL (2009)
The ubiquitin landscape at DNA double-strand breaks
Troy E. Messick et al.
JOURNAL OF CELL BIOLOGY (2009)
XRCC2 and XRCC3 Regulate the Balance between Short- and Long-Tract Gene Conversions between Sister Chromatids
Ganesh Nagaraju et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
A Selective Requirement for 53BP1 in the Biological Response to Genomic Instability Induced by Brca1 Deficiency
Liu Cao et al.
MOLECULAR CELL (2009)
Multiple functions of MRN in end-joining pathways during isotype class switching
Maria Dinkelmann et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
Anyong Xie et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair
Puck Knipscheer et al.
SCIENCE (2009)
A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation
P. J. Hastings et al.
PLOS GENETICS (2009)
Mechanism of eukaryotic homologous recombination
Joseph San Filippo et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination
Louise J. Barber et al.
CELL (2008)
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair
R. Scott Williams et al.
CELL (2008)
Mechanism of replication-coupled DNA interstrand crosslink repair
Markus Raeschle et al.
CELL (2008)
Break-induced replication - What is it and what is it for?
Bertrand Llorente et al.
CELL CYCLE (2008)
APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation
Chloe J. Macrae et al.
DNA REPAIR (2008)
Homologous recombination in real time: DNA strand exchange by RecA
Thijn van der Heijden et al.
MOLECULAR CELL (2008)
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
Aaron A. Goodarzi et al.
MOLECULAR CELL (2008)
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Eleni P. Mimitou et al.
NATURE (2008)
CDK targets Sae2 to control DNA-end resection and homologous recombination
Pablo Huertas et al.
NATURE (2008)
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
Nadya Dimitrova et al.
NATURE (2008)
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
Zhucheng Chen et al.
NATURE (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms
Celia Payen et al.
PLOS GENETICS (2008)
Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair
Nicole Bennardo et al.
PLOS GENETICS (2008)
A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
Jennifer A. Lee et al.
CELL (2007)
Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair
Anyong Xie et al.
MOLECULAR CELL (2007)
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
Bettina M. Lengsfeld et al.
MOLECULAR CELL (2007)
Human CtIP promotes DNA end resection
Alessandro A. Sartori et al.
NATURE (2007)
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
Oliver Limbo et al.
MOLECULAR CELL (2007)
IgH class switching and translocations use a robust non-classical end-joining pathway
Catherine T. Yan et al.
NATURE (2007)
Break-induced replication and telomerase-independent telomere maintenance require Pol32
John R. Lydeard et al.
NATURE (2007)
Positional stability of single double-strand breaks in mammalian cells
Evi Soutoglou et al.
NATURE CELL BIOLOGY (2007)
Template switching during break-induced replication
Catherine E. Smith et al.
NATURE (2007)
Replisome assembly and the direct restart of stalled replication forks
Ryan C. Heller et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C
Ganesh Nagaraju et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Mechanism of homologous recombination: mediators and helicases take on regulatory functions
Patrick Sung et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks
Kyoko Nakamura et al.
DNA REPAIR (2006)
γH2AX and MDC1:: Anchoring the DNA-damage-response machinery to broken chromosomes
M Stucki et al.
DNA REPAIR (2006)
On the mechanism of gene amplification induced under stress in Escherichia coli
Andrew Slack et al.
PLOS GENETICS (2006)
The RecA binding locus of RecBCD is a general domain for recruitment of DNA strand exchange proteins
M Spies et al.
MOLECULAR CELL (2006)
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
P Ahnesorg et al.
CELL (2006)
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
D Buck et al.
CELL (2006)
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
M Lopes et al.
MOLECULAR CELL (2006)
Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier
S Lambert et al.
CELL (2005)
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
JH Lee et al.
SCIENCE (2005)
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
HJ Yang et al.
NATURE (2005)
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
JH Lee et al.
SCIENCE (2004)
Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains
JA Aten et al.
SCIENCE (2004)
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
Y Aylon et al.
EMBO JOURNAL (2004)
The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm
N Shima et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
XC Yu et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Genetic steps of mammalian homologous repair with distinct mutagenic consequences
JM Stark et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila
M McVey et al.
GENETICS (2004)
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
G Ira et al.
NATURE (2004)
In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination
N Sugawara et al.
MOLECULAR CELL (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
DNA helicase Srs2 disrupts the Rad51 presynaptic filament
L Krejci et al.
NATURE (2003)
An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication
V Costanzo et al.
MOLECULAR CELL (2003)
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
LS Symington
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2002)
Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
M Frank-Vaillant et al.
MOLECULAR CELL (2002)
Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences
G Ira et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
JM Sogo et al.
SCIENCE (2002)
Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III
T Caspari et al.
GENES & DEVELOPMENT (2002)
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
AJ Pierce et al.
GENES & DEVELOPMENT (2001)
ATR and ATRIP: Partners in checkpoint signaling
D Cortez et al.
SCIENCE (2001)
The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations
DO Ferguson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Ku recruits the XRCC4-ligase IV complex to DNA ends
SAN McElhinny et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)