4.4 Article

Diarylpropanes from Horsfieldia kingii

Journal

NATURAL PRODUCT RESEARCH
Volume 35, Issue 7, Pages 1127-1133

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2019.1643858

Keywords

Horsfielenide; flavonoids; Horsfieldia kingii

Funding

  1. National Natural Science Foundation of China [31460086]
  2. Science and Technology Program of Yunnan Province [2014FD013]
  3. Scientific Research Program of the Education Department of Yunnan Province [2014Z047]

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Three new diarylpropanes were isolated from the twigs and leaves of Horsfieldia kingii, along with three known compounds. Spectroscopic analysis confirmed their structures. However, bioactive evaluation showed that the new compounds were inactive in inhibiting DDC enzyme.
Three new diarylpropanes (1-3), including two diarylpropane glycosides, and three known ones, were isolated from 70% aqueous acetone extract of the twigs and leaves of Horsfieldia kingii. Their structures were elucidated by spectroscopic analysis. Bioactive evaluation of inhibition on DDC enzyme assay showed that the new compounds were inactive. [GRAPHICS] .

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