Journal
NATURAL PRODUCT COMMUNICATIONS
Volume 14, Issue 7, Pages -Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/1934578X19862893
Keywords
Aedes aegypti; plant extract; larvicidal compounds; vector control
Categories
Funding
- CAPES
- Research Institute of Natural Products
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Aedes aegypti is the main transmitter of several arboviruses, mainly dengue. It occurs, recently, in more than 100 countries and majority of the world population lives in areas of mosquito incidence, marking its control relevant and necessary. Presently, the main form of vector control is the use of synthetic insecticides; however, its continuous application has led to inefficiency due to resistance development. Based on this fact, the insecticides from natural sources appear as a friendly alternative for man and the environment. This study provides an overview of the larvicidal compounds isolated from plant extracts while controlling A. aegypti, in the previous 6 years (2013-2018), and aims to impart more knowledge regarding the described metabolites and to encourage the search for new bioactive compounds. In addition, the proposals for mechanisms of action and structure-activity relationships that may justify the larvicidal potential are also discussed.
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