4.4 Article

Empowering statistical methods for cellular and molecular biologists

Journal

MOLECULAR BIOLOGY OF THE CELL
Volume 30, Issue 12, Pages 1359-1368

Publisher

AMER SOC CELL BIOLOGY
DOI: 10.1091/mbc.E15-02-0076

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Funding

  1. National Science Foundation Award [MCB-1518314]
  2. National Institute of General Medical Sciences of the National Institutes of Health [R01GM026132, R01GM026338]
  3. Gladstone Institutes

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We provide guidelines for using statistical methods to analyze the types of experiments reported in cellular and molecular biology journals such as Molecular Biology of the Cell. Our aim is to help experimentalists use these methods skillfully, avoid mistakes, and extract the maximum amount of information from their laboratory work. We focus on comparing the average values of control and experimental samples. A Supplemental Tutorial provides examples of how to analyze experimental data using R software.

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