Journal
MICROFLUIDICS AND NANOFLUIDICS
Volume 23, Issue 7, Pages -Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s10404-019-2258-2
Keywords
Modular systems; Microfluidics; 3D printing; Droplet generation
Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [2017R1A2B2006964]
- National Research Foundation of Korea [2017R1A2B2006964] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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We designed a modular microfluidic system for generating droplets using a three-dimensional (3D) printer. This system was manufactured as a modular system with multipurpose droplet generation flexibility. The various types of emulsion droplets can be generated by changing the combination of the incorporated modules. All modules are interconnected based on a novel coupling system that facilitates assembly and disassembly, and leakages do not occur even for pressures of the order of40kPa. We demonstrate the capacity of the system to generate emulsion droplets, ranging from single to complicated dual-core double-emulsion droplets. Droplet sizes in the range of 50-500m were obtained by controlling the flow rate and the generation frequency in the range of 1-100Hz. Furthermore, an electrode module was developed to demonstrate different electrohydrodynamic phenomena, such as the shape deformation, coalescence, breakup, and others. This 3D printed modular microfluidic system makes it possible to meet the needs of the end-user, and can be applied to bioassays, material synthesis, and other applications.
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