Journal
MEDICAL MYCOLOGY
Volume 57, Issue -, Pages S259-S266Publisher
OXFORD UNIV PRESS
DOI: 10.1093/mmy/myy159
Keywords
fungi; proximity ligation assay; T2 Candida; lateral flow assay; next generation sequencing; risk stratification
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The field of diagnostic mycology represents much more than culture and microscopy and is rapidly embracing novel techniques and strategies to help overcome the limitations of conventional approaches. Commercial molecular assays increase the applicability of PCR testing and may identify markers of antifungal resistance, which are of great clinical concern. Lateral flow assays simplify testing and turn-around time, with potential for point of care testing, while proximity ligation assays embrace the sensitivity of molecular testing with the specificity of antibody detection. The first evidence of patient risk stratification is being described and together with the era of next generation sequencing represents an exciting time in mycology.
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