Journal
APPLIED SURFACE SCIENCE
Volume 366, Issue -, Pages 404-409Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.apsusc.2016.01.133
Keywords
Nanocrystalline cellulose (NCC); Cationic surfactant cetyltrimethylammonium bromide (CTMAB); Luteolin (LUT); Luteoloside (LUS); Drug delivery
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Funding
- Support Plan of Science and Technology Innovation team in Universities and Colleges in Henan Province of China [14IRTSTHN030]
- Key Project of Science and Technology Research in Education Department of Henan Province in China [14A150011]
- Key Technology Research Program of Henan Province in China [152102210257]
- National Science Foundation of China [U1204304]
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In this work, torispherical nanocrystalline cellulose (NCC) was synthesized, and firstly modified with a cationic surfactant cetyltrimethylammonium bromide (CTMAB). It was proved that the kinetics of NCC adsorbing CTMAB followed the pseudo-second-order kinetics equation, and the adsorption isotherm model followed Freundlich which was multi molecular layer adsorption model. The morphology and structure of NCC and CTMAB-coated NCC were characterized by transmission electron microscopy (TEM) and X-ray powder diffraction (XRD). Stabilities of NCC and CTMAB-coated NCC were assayed by zeta potential. The results showed that NCC in CTMAB solution was well-dispersed and stable. Moreover, the drug loading and release performance of CTMAB-coated NCC were studied using luteolin (LUT) and luteoloside (LUS) as model drugs. (C) 2016 Elsevier B.V. All rights reserved.
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