Use of the monodisperse Pt/Ni@rGO nanocomposite synthesized by ultrasonic hydroxide assisted reduction method in electrochemical nonenzymatic glucose detection

An electrochemical non-enzymatic sensor was developed for the detection of glucose based on an electrode modified with monodisperse platinum-nickel nanocomposites-decorated on reduced graphene oxide (Pt/NigrGO) which was synthesized using a new ultrasonic hydroxide assisted reduction method. Because the nano composites prepared by using NaOH (OH- ligands) are much smaller nanocomposites on the supports compared to the ones without OH- ligands. Such a monodisperse Pt/Ni@rGO nanocomposites-based electrode exhibited a high electrochemical activity for electrocatalytic oxidation of glucose in alkaline solution. Amperometric analysis showed a glucose sensitivity of 171.92 mu A/mM cm(2) of, the detection limit of 6.3 mu M and a linear range of 0.02-5.0 mM glucose concentration. Fabricated sensor platform demonstrated long-term stability and good reproducibility, in addition to high selectivity.