Journal
MAGNETIC RESONANCE IMAGING
Volume 60, Issue -, Pages 122-129Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mri.2019.04.004
Keywords
Chemical exchange saturation transfer; MRI; Multi-slice; Spatiotemporal encoding
Funding
- National Natural Science Foundation of China [11775184, 11474236, 81671674]
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Chemical exchange saturation transfer (CEST) imaging is an important magnetic resonance molecular imaging technology. However, long acquisition time limits its clinical application, especially when multi-slice CEST imaging is needed. Though single-shot EPI can be used to accelerate CEST imaging, images are often distorted under inhomogeneous magnetic fields. In this work, we propose a new method called CEST-SeSPEN for ultrafast multi-slice LEST imaging based on segmented spatiotemporally encoded (SeSPEN) MRI. Experiments were performed on creatine phantom and hen egg. The results show that CEST-SeSPEN can provide good CEST contrast images. Its acquisition time is much shorter than other multi-slice CEST methods currently available. It may be used in challenging situation where high temporal resolution and robustness to field inhomogeneity are vital.
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