Journal
LASERS IN SURGERY AND MEDICINE
Volume 51, Issue 10, Pages 882-886Publisher
WILEY
DOI: 10.1002/lsm.23126
Keywords
CO2 laser; vagina; pelvic floor dysfunctions; fractional laser
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Funding
- Economic Development and Innovation Operational Program Grant of the European Union and Hungary [GINOP-2.1.1-15-2016-00783]
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Background and Objectives To assess the improvement on pelvic floor distress (PFD)-related urogenital symptoms using validated questionnaires after intravaginal CO2 laser treatment. Study Design/Materials and Methods Forty postmenopausal women with genitourinary symptoms of menopause (GSM) were enrolled into this prospective cohort study and underwent vaginal laser treatment using MonaLisa Touch (R) fractional CO (2) laser system. Patients received three vaginal laser treatments with 360 degrees probe 4 weeks apart. A three-component Pelvic Floor Distress Inventory (PFDI-20) validated questionnaire was filled out by each patient before each session and 4 weeks after the final treatment. Wilcoxon rank sum test was used to compare the before and after treatment scores. Results Pelvic Organ Prolapse Distress Inventory (POPDI-6) scores were not significantly different after the first treatment compared with baseline (mean +/- standard deviation [SD], 21 +/- 18 vs. 17 +/- 15, P = 0.44). However, each subsequent treatment resulted in further, statistically significant improvement in symptom scores (14 +/- 15, P = 0.03 and 13 +/- 13, P = 0.01, after the second and third treatments, respectively). Similarly, Urinary Distress Inventory (UDI-6) scores were not significantly different after the first laser treatment (mean +/- SD, 36 +/- 25 vs. 29 +/- 23, P = 0.36). After the second and third treatments there were significant improvement in the standardized scores (24 +/- 20, P = 0.03 and 22 +/- 21, P = 0.01). Colorectal-Anal Distress Inventory (CRADI-8) scores did not change significantly after three laser treatments. Conclusions Three sessions of microablative fractional CO2 vaginal laser treatment significantly improves patient reported urinary and pelvic organ prolapse symptoms. Lasers Surg. Med. (c) 2019 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.
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