4.7 Review

Parkinson's disease in the Western Pacific Region

Journal

LANCET NEUROLOGY
Volume 18, Issue 9, Pages 865-879

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/S1474-4422(19)30195-4

Keywords

-

Funding

  1. University of Malaya Parkinson's Disease and Movement Disorders Research Program Fund [PV035-2017]
  2. National Medical Research Council, Singapore (STaR)
  3. National Medical Research Council, Singapore (Singapore Parkinson's Disease Programme Grant [SPARK 1])
  4. National Medical Research Council, Singapore (Singapore Parkinson's Disease Programme Grant [SPARK 2])

Ask authors/readers for more resources

1.8 billion people of diverse ethnicities and cultures live in the Western Pacific Region. The increasing longevity of populations in this region is a major contributor to the exponential increase in Parkinson's disease prevalence worldwide. Differences exist between Parkinson's disease in the Western Pacific Region and in Europe and North America that might provide important insights into our understanding of the disease and approaches to management. For example, some genetic factors (such as LRRK2 mutations or variants) differ, environmental exposures might play differential roles in modulating the risk of Parkinson's disease, and fewer dyskinesias are reported, with some differences in the profile of non-motor symptoms and comorbidities. Gaps in awareness of the disease and inequitable access to treatments pose challenges. Further improvements in infrastructure, clinical governance, and services, and concerted collaborative efforts in training and research, including greater representation of the Western Pacific Region in clinical trials, will improve care of patients with Parkinson's disease in this region and beyond.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available