Magnetic mesoporous poly-melamine-formaldehyde: an efficient and recyclable catalyst for straightforward one-pot synthesis of imidazo[1,2-a]pyridines

Magnetically separable mesoporous poly-melamine-formaldehyde nanocomposite (Fe3O4@mPMF) has been synthesized and characterized by FTIR spectroscopy, SEM, XRD spectroscopy and EDS. The magnetically separable Fe3O4@mPMF catalyst had excellent efficiency for the synthesis a wide diversity of imidazo[1,2-a]pyridines by a three-component reaction of a 2-aminopyridine, aldehyde and isocyanide in good-to-excellent yields within a short reaction time, through an environmental friendliness and straightforward procedure. The nanocomposite that is easily recoverable and also found to be reusable can be recovered and reused when the reaction is completed for several times without distinct deterioration in catalytic activity. [GRAPHICS] .