Journal
JOURNAL OF ELECTRONIC MATERIALS
Volume 48, Issue 10, Pages 6231-6239Publisher
SPRINGER
DOI: 10.1007/s11664-019-07414-0
Keywords
Nanocomposite; conducting polymer; biosensor; nanorod; CeO2
Categories
Funding
- Vietnam National Foundation for Science and Technology Development [103.02-2015.50]
Ask authors/readers for more resources
A facile label-free DNA sensor based on cerium oxide nanorods decorated with polypyrrole nanoparticles (CeO2-NRs/Ppy-NPs) matrix has been developed for detection of Salmonella. The sensor was fabricated by hydrothermal synthesis of CeO2-NRs on the microelectrode surface followed by in situ chemical oxidative polymerization of pyrrole on the CeO2-NRs to prepare a CeO2-NR/Ppy-NPs electrode. Single-stranded DNA (ssDNA) sequences were immobilized onto the modified microelectrode by covalent attachment. The properties of the material were explored by field-emission scanning electron microscopy, x-ray diffraction analysis, and Fourier-transform infrared spectroscopy techniques. The response of the DNA biosensor was investigated by electrochemical impedance spectroscopy with [Fe(CN)(6)](3-/4-) as redox probe. The results showed that the response of the DNA biosensor exhibited good linearity within the range of 1.0 x 10(-9) mol L-1 to 1.0 x 10(-6) mol L-1 with sensitivity of 14.7 x 10(6) omega/mol L-1 cm(-1). The limit of detection and limit of quantification of the DNA biosensor were low, with values of 2.86.10(-7) mol L-1 and 9.56.10(-7) mol L-1, respectively.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available