Related references
Note: Only part of the references are listed.Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models
Mychael V. Lourenco et al.
NATURE MEDICINE (2019)
Effect of exercise training on liver function in adults who are overweight or exhibit fatty liver disease: a systematic review and meta-analysis
N. A. Smart et al.
BRITISH JOURNAL OF SPORTS MEDICINE (2018)
Effects of Physical Exercise on Alzheimer's Disease Biomarkers: A Systematic Review of Intervention Studies
Kristian Steen Frederiksen et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Microglia in Alzheimer's disease
David V. Hansen et al.
JOURNAL OF CELL BIOLOGY (2018)
Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology
Ronald C. Petersen et al.
NEUROLOGY (2018)
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
Clifford R. Jack et al.
ALZHEIMERS & DEMENTIA (2018)
World Wide Fingers will advance dementia prevention
Miia Kivipelto et al.
LANCET NEUROLOGY (2018)
Exercise decreases BACE and APP levels in the hippocampus of a rat model of Alzheimer's disease
Karim A. Alkadhi et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2018)
Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
Steven E. Arnold et al.
NATURE REVIEWS NEUROLOGY (2018)
Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease
Tracy Butler et al.
NEUROBIOLOGY OF AGING (2018)
Oxidant/Antioxidant Imbalance in Alzheimer's Disease: Therapeutic and Diagnostic Prospects
Joanna Wojsiat et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: A cluster-randomised controlled trial
Clive Ballard et al.
PLOS MEDICINE (2018)
Elucidating the Interactive Roles of Glia in Alzheimer's Disease Using Established and Newly Developed Experimental Models
Heejung Chun et al.
FRONTIERS IN NEUROLOGY (2018)
Signaling and Function of Interleukin-2 in T Lymphocytes
Sarah H. Ross et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 36 (2018)
Molecular Bases of Alzheimer's Disease and Neurodegeneration: The Role of Neuroglia
Antonina Luca et al.
AGING AND DISEASE (2018)
A Remote Intervention to Prevent or Delay Cognitive Impairment in Older Adults: Design, Recruitment, and Baseline Characteristics of the Virtual Cognitive Health (VC Health) Study
Nicholas Bott et al.
JMIR RESEARCH PROTOCOLS (2018)
Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease
Danielle S. Davies et al.
BRAIN PATHOLOGY (2017)
Associations Between Hepatic Functions and Plasma Amyloid-Beta Levels-Implications for the Capacity of Liver in Peripheral Amyloid-Beta Clearance
Ye-Ran Wang et al.
MOLECULAR NEUROBIOLOGY (2017)
Exercise-stimulated glucose uptake - regulation and implications for glycaemic control
Lykke Sylow et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
A 3-Month Aerobic Training Program Improves Brain Energy Metabolism in Mild Alzheimer's Disease: Preliminary Results from a Neuroimaging Study
Christian-Alexandre Castellano et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition
Chia-Chen Liu et al.
JOURNAL OF NEUROSCIENCE (2017)
Dementia prevention, intervention, and care
Gill Livingston et al.
LANCET (2017)
Glial contributions to neurodegeneration in tauopathies
Cheryl E. G. Leyns et al.
MOLECULAR NEURODEGENERATION (2017)
A systemic view of Alzheimer disease - insights from amyloid-β metabolism beyond the brain
Jun Wang et al.
NATURE REVIEWS NEUROLOGY (2017)
Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment
Mark A. Espeland et al.
NEUROLOGY (2017)
Exercise Training Increases Parietal Lobe Cerebral Blood Flow in Chronic Stroke: An Observational Study
Andrew D. Robertson et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
Alzheimer's Disease and the Amyloid-β Peptide
M. Paul Murphy et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial
Jill K. Morris et al.
PLOS ONE (2017)
Interleukin-6 increases the expression and activity of insulin-degrading enzyme
Mirian A. Kurauti et al.
SCIENTIFIC REPORTS (2017)
Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease
Cheril Tapia-Rojas et al.
BRAIN PATHOLOGY (2016)
Oxidative Stress Is a Central Target for Physical Exercise Neuroprotection Against Pathological Brain Aging
Yoelvis Garcia-Mesa et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2016)
In Vivo Imaging of Human Neuroinflammation
Daniel S. Albrecht et al.
ACS CHEMICAL NEUROSCIENCE (2016)
Exercise as a pro-cognitive, pro-neurogenic and anti-inflammatory intervention in transgenic mouse models of Alzheimer's disease
Sinead M. Ryan et al.
AGEING RESEARCH REVIEWS (2016)
Modifiable Risk Factors and Brain Positron Emission Tomography Measures of Amyloid and Tau in Nondemented Adults with Memory Complaints
David A. Merrill et al.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2016)
Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease?
Olga Pivovarova et al.
ANNALS OF MEDICINE (2016)
Cerebrospinal Fluid Amyloid Beta and Tau Concentrations Are Not Modulated by 16 Weeks of Moderate- to High-Intensity Physical Exercise in Patients with Alzheimer Disease
Camilla Steen Jensen et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2016)
Depression as a risk factor for Alzheimer's disease: Genes, steroids, cytokines and neurogenesis - What do we need to know?
Joe Herbert et al.
FRONTIERS IN NEUROENDOCRINOLOGY (2016)
Changes in insulin and insulin signaling in Alzheimer's disease: cause or consequence?
Molly Stanley et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Effects of Exercise on Cognition: The Finnish Alzheimer Disease Exercise Trial: A Randomized, Controlled Trial
Hannareeta Ohman et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2016)
Physical Activity and Alzheimer Disease: A Protective Association
Alejandro Santos-Lozano et al.
MAYO CLINIC PROCEEDINGS (2016)
Late running is not too late against Alzheimer's pathology
Arne Herring et al.
NEUROBIOLOGY OF DISEASE (2016)
Higher brain BDNF gene expression is associated with slower cognitive decline in older adults
Aron S. Buchman et al.
NEUROLOGY (2016)
Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate?
Sinead M. Ryan et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2016)
Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice
Montasir Elahi et al.
NEUROSCIENCE LETTERS (2016)
Acute Exercise Improves Insulin Clearance and Increases the Expression of Insulin-Degrading Enzyme in the Liver and Skeletal Muscle of Swiss Mice
Mirian A. Kurauti et al.
PLOS ONE (2016)
Mechanisms of Aβ Clearance and Degradation by Glial Cells
Miriam Ries et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study
Monika Puzianowska-Kuznicka et al.
IMMUNITY & AGEING (2016)
Redox Mechanism of Reactive Oxygen Species in Exercise
Feng He et al.
FRONTIERS IN PHYSIOLOGY (2016)
Role of oxidative stress in Alzheimer's disease
Wen-Juan Huang et al.
BIOMEDICAL REPORTS (2016)
Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer's Disease: A Randomized Controlled Trial
Kristine Hoffmann et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Impact of aerobic and anaerobic exercise training on oxidative stress and antioxidant defense in athletes
Song-Young Park et al.
JOURNAL OF EXERCISE REHABILITATION (2016)
Traumatic brain injury as a risk factor for Alzheimer's disease: current knowledge and future directions
Kristen Dams-O'Connor et al.
NEURODEGENERATIVE DISEASE MANAGEMENT (2016)
Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease
Yang Xiang et al.
ACTA NEUROPATHOLOGICA (2015)
Lower cerebral blood flow is related to more severe cognitive impairment in patients with dementia due to Alzheimer's disease
Annebet Leeuwis et al.
Alzheimers & Dementia (2015)
Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective
Matthew Baumgart et al.
ALZHEIMERS & DEMENTIA (2015)
Low Cardiac Index Is Associated With Incident Dementia and Alzheimer Disease The Framingham Heart Study
Angela L. Jefferson et al.
CIRCULATION (2015)
Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer's Disease: A Systematic Review and Meta-Analysis of Treatment Effect
Marina Miguel-Alvarez et al.
DRUGS & AGING (2015)
Blood Pressure Is Not Associated With Cerebral Blood Flow in Older Persons
Jessica C. Foster-Dingley et al.
HYPERTENSION (2015)
What are the Benefits of Exercise for Alzheimer's Disease? A Systematic Review of the Past 10 Years
Salma S. S. Hernandez et al.
JOURNAL OF AGING AND PHYSICAL ACTIVITY (2015)
Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review
Thierry Paillard et al.
JOURNAL OF CLINICAL NEUROLOGY (2015)
A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor
Kristin L. Szuhany et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2015)
Physical Activity and Amyloid- Brain Levels in Elderly Adults with Intact Cognition and Mild Cognitive Impairment
Philipe de Souto Barreto et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2015)
Physical Activity as Protective Factor against Dementia: A Prospective Population-Based Study (NEDICES)
Sara Llamas-Velasco et al.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY (2015)
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
Tiia Ngandu et al.
LANCET (2015)
Immune attack: the role of inflammation in Alzheimer disease
Frank L. Heppner et al.
NATURE REVIEWS NEUROSCIENCE (2015)
Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice
Tzu-Wei Lin et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2015)
TREADMILL EXERCISE ENHANCES SYNAPTIC PLASTICITY, BUT DOES NOT ALTER β-AMYLOID DEPOSITION IN HIPPOCAMPI OF AGED APP/PS1 TRANSGENIC MICE
G. Zhao et al.
NEUROSCIENCE (2015)
The effect of cognitive-motor dual-task training on cognitive function and plasma amyloid β peptide 42/40 ratio in healthy elderly persons: a randomized controlled trial
Hisayo Yokoyama et al.
BMC GERIATRICS (2015)
Impact of Oxidative Stress on Exercising Skeletal Muscle
Peter Steinbacher et al.
BIOMOLECULES (2015)
Amyloid-β Efflux from the Central Nervous System into the Plasma
Kaleigh Filisa Roberts et al.
ANNALS OF NEUROLOGY (2014)
The overlap between vascular disease and Alzheimer's disease - lessons from pathology
Johannes Attems et al.
BMC MEDICINE (2014)
Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment
Niklas Mattsson et al.
BRAIN (2014)
2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
Robert H. Eckel et al.
CIRCULATION (2014)
Type 3 diabetes is sporadic Alzheimer's disease: Mini-review
Suzanne M. de la Monte
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2014)
Regular and moderate exercise initiated in middle age prevents age-related amyloidogenesis and preserves synaptic and neuroprotective signaling in mouse brain cortex
Silvia Di Loreto et al.
EXPERIMENTAL GERONTOLOGY (2014)
Heart Diseases and Long-Term Risk of Dementia and Alzheimer's Disease: A Population-Based CAIDE Study
Minna Rusanen et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Claudio Franceschi et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Potential for primary prevention of Alzheimer's disease: an analysis of population-based data (vol 13, pg 788, 2014)
S. Norton et al.
LANCET NEUROLOGY (2014)
Body Fluid Cytokine Levels in Mild Cognitive Impairment and Alzheimer's Disease: a Comparative Overview
Frederic Brosseron et al.
MOLECULAR NEUROBIOLOGY (2014)
Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice
Odochi Ohia-Nwoko et al.
MOLECULAR NEURODEGENERATION (2014)
Physical activity attenuates age-related biomarker alterations in preclinical AD
Ozioma C. Okonkwo et al.
NEUROLOGY (2014)
Chronic kidney disease is associated with dementia independent of cerebral small-vessel disease
Kaori Miwa et al.
NEUROLOGY (2014)
Exercise-Induced Neuroprotection of Hippocampus in APP/PS1 Transgenic Mice via Upregulation of Mitochondrial 8-Oxoguanine DNA Glycosylase
Hai Bo et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
Gernot Kleinberger et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Oxidative stress in Alzheimer's disease
Zhichun Chen et al.
NEUROSCIENCE BULLETIN (2014)
Alzheimer's disease drug-development pipeline: few candidates, frequent failures
Jeffrey L. Cummings et al.
ALZHEIMERS RESEARCH & THERAPY (2014)
Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease
J. Carson Smith et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Frontotemporal dementia: diagnosis, deficits and management
Nicholas T. Bott et al.
NEURODEGENERATIVE DISEASE MANAGEMENT (2014)
Potential for primary prevention of Alzheimer's disease: an analysis of population-based data
Sam Norton et al.
LANCET NEUROLOGY (2014)
Microglia actions in Alzheimer’s disease
Stefan Prokop et al.
ACTA NEUROPATHOLOGICA (2013)
Cerebral blood flow and cerebrovascular reactivity at rest and during sub-maximal exercise: Effect of age and 12-week exercise training
Carissa J. Murrell et al.
AGE (2013)
Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice
Eun-Bum Kang et al.
APOPTOSIS (2013)
Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice
Hui-li Liu et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer's Disease
Bin Zhang et al.
CELL (2013)
Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
Christiane D. Wrann et al.
CELL METABOLISM (2013)
Dyslipidemia and the Risk of Alzheimer's Disease
Christiane Reitz
CURRENT ATHEROSCLEROSIS REPORTS (2013)
Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I
Francesco Paneni et al.
EUROPEAN HEART JOURNAL (2013)
Intensive Blood Pressure Lowering Increases Cerebral Blood Flow in Older Subjects With Hypertension
Dinesh Tryambake et al.
HYPERTENSION (2013)
Life-Long Aerobic Exercise Preserved Baseline Cerebral Blood Flow but Reduced Vascular Reactivity to CO2
Binu P. Thomas et al.
JOURNAL OF MAGNETIC RESONANCE IMAGING (2013)
Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing
B. M. Brown et al.
MOLECULAR PSYCHIATRY (2013)
Deciphering the mechanism underlying late-onset Alzheimer disease
Dimitrije Krstic et al.
NATURE REVIEWS NEUROLOGY (2013)
Changes in vascular factors 28 years from midlife and late-life cortical thickness
Miika Vuorinen et al.
NEUROBIOLOGY OF AGING (2013)
Inflammation and clinical presentation in neurodegenerative disease: a volatile relationship
Brianne Magouirk Bettcher et al.
NEUROCASE (2013)
Meta-analysis of amyloid-cognition relations in cognitively normal older adults
Trey Hedden et al.
NEUROLOGY (2013)
Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
Liesi E. Hebert et al.
NEUROLOGY (2013)
Exercise and Sodium Butyrate Transform a Subthreshold Learning Event into Long-Term Memory via a Brain-Derived Neurotrophic factor-Dependent Mechanism
Karlie A. Intlekofer et al.
NEUROPSYCHOPHARMACOLOGY (2013)
Treadmill exercise slows cognitive deficits in aging rats by antioxidation and inhibition of amyloid production
Feng Yu et al.
NEUROREPORT (2013)
Glucose Levels and Risk of Dementia
Paul K. Crane et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology
Grietje Krabbe et al.
PLOS ONE (2013)
Continuation of Exercise Is Necessary to Inhibit High Fat Diet-Induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice
Masato Maesako et al.
PLOS ONE (2013)
Chronic Kidney Disease and Cognitive Impairment: A Systematic Review and Meta-Analysis
Thorleif Etgen et al.
AMERICAN JOURNAL OF NEPHROLOGY (2012)
Effect of lifestyle activities on alzheimer disease biomarkers and cognition
Prashanthi Vemuri et al.
ANNALS OF NEUROLOGY (2012)
Association of Lifetime Cognitive Engagement and Low β-Amyloid Deposition
Susan M. Landau et al.
ARCHIVES OF NEUROLOGY (2012)
Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition
Denise Head et al.
ARCHIVES OF NEUROLOGY (2012)
Elevation of glutathione as a therapeutic strategy in Alzheimer disease
Chava B. Pocernich et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Wheel running attenuates microglia proliferation and increases expression of a proneurogenic phenotype in the hippocampus of aged mice
Rachel A. Kohman et al.
BRAIN BEHAVIOR AND IMMUNITY (2012)
Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?
Ralph J. DeBerardinis et al.
CELL (2012)
Anti-Inflammatory Effects of Physical Activity in Relationship to Improved Cognitive Status in Humans and Mouse Models of Alzheimers Disease
Alexis M. Stranahan et al.
Current Alzheimer Research (2012)
Both resistance- and endurance-type exercise reduce the prevalence of hyperglycaemia in individuals with impaired glucose tolerance and in insulin-treated and non-insulin-treated type 2 diabetic patients
J. -W. van Dijk et al.
DIABETOLOGIA (2012)
Midlife Blood Pressure, Plasma β-Amyloid, and the Risk for Alzheimer Disease The Honolulu Asia Aging Study
Nilay S. Shah et al.
HYPERTENSION (2012)
Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice
Masato Maesako et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cognitive reserve in ageing and Alzheimer's disease
Yaakov Stern
LANCET NEUROLOGY (2012)
Antioxidant Therapies for Alzheimer's Disease
Ye Feng et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Reisa A. Sperling et al.
ALZHEIMERS & DEMENTIA (2011)
The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Marilyn S. Albert et al.
ALZHEIMERS & DEMENTIA (2011)
Chronic exercise ameliorates the neuroinflammation in mice carrying NSE/htau23
Yea-Hyun Leem et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Exercise-induced myokines and their role in chronic diseases
Bente K. Pedersen
BRAIN BEHAVIOR AND IMMUNITY (2011)
Selective improvement of cognitive function in adult and aged APP/PS1 transgenic mice by continuous non-shock treadmill exercise
Hsing-Chieh Ke et al.
BRAIN RESEARCH (2011)
Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice
Dan Ehninger et al.
CELL AND TISSUE RESEARCH (2011)
Current and Emerging Drug Treatment Options for Alzheimerʼs Disease
Nathan Herrmann et al.
DRUGS (2011)
Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice
Yoelvis Garcia-Mesa et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease
Kazuma Murakami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
Heiko Braak et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
The projected effect of risk factor reduction on Alzheimer's disease prevalence
Deborah E. Barnes et al.
LANCET NEUROLOGY (2011)
Epidemiology of Alzheimer disease
Christiane Reitz et al.
NATURE REVIEWS NEUROLOGY (2011)
Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging
J. Eric Ahlskog et al.
MAYO CLINIC PROCEEDINGS (2011)
Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology
Karim Belarbi et al.
NEUROBIOLOGY OF DISEASE (2011)
Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease
J. Li et al.
NEUROLOGY (2011)
Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults: Guidance for Prescribing Exercise
Carol Ewing Garber et al.
MEDICINE & SCIENCE IN SPORTS & EXERCISE (2011)
Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease
Hyun-Sub Um et al.
NEUROSCIENCE RESEARCH (2011)
Exercise training increases size of hippocampus and improves memory
Kirk I. Erickson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity
Stephane P. Poulin et al.
PSYCHIATRY RESEARCH-NEUROIMAGING (2011)
Vascular Contributions to Cognitive Impairment and Dementia A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association
Philip B. Gorelick et al.
STROKE (2011)
Physical Activity in the Prevention of Chronic Kidney Disease
Craig S. Stump
CARDIORENAL MEDICINE (2011)
Neuropathological Alterations in Alzheimer Disease
Alberto Serrano-Pozo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
APP processing in Alzheimer's disease
Yun-Wu Zhang et al.
MOLECULAR BRAIN (2011)
Innate and adaptive immunosenescence
Shradha Agarwal et al.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2010)
Systematic Review: Factors Associated With Risk for and Possible Prevention of Cognitive Decline in Later Life
Brenda L. Plassman et al.
ANNALS OF INTERNAL MEDICINE (2010)
Exercise and Alzheimer's Disease Biomarkers in Cognitively Normal Older Adults
Kelvin Y. Liang et al.
ANNALS OF NEUROLOGY (2010)
Effects of Aerobic Exercise on Mild Cognitive Impairment A Controlled Trial
Laura D. Baker et al.
ARCHIVES OF NEUROLOGY (2010)
Pathological roles of MAPK signaling pathways in human diseases
Eun Kyung Kim et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Reduction of Cerebral Oxidative Stress Following Environmental Enrichment in Mice with Alzheimer-Like Pathology
Arne Herring et al.
BRAIN PATHOLOGY (2010)
Non-Steroidal Anti-Inflammatory Drugs and Alzheimer's Disease: The Epidemiological Evidence
C. A. Szekely et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2010)
Aging of the innate immune system
Albert C. Shaw et al.
CURRENT OPINION IN IMMUNOLOGY (2010)
Coupling Aging Immunity with a Sedentary Lifestyle: Has the Damage Already Been Done? - A Mini-Review
Richard J. Simpson et al.
GERONTOLOGY (2010)
The combination of exercise training and α-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer's disease in NSE/APPsw-transgenic mice
Joon Y. Cho et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2010)
Aerobic Exercise Improves Cognition for Older Adults with Glucose Intolerance, A Risk Factor for Alzheimer's Disease
Laura D. Baker et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Plasma Aβ42 and Aβ40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study
T. T. Seppala et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)
Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex
Mubeen A. Ansari et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Clifford R. Jack et al.
LANCET NEUROLOGY (2010)
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
Giovanni Targher et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Aerobic Exercise and Neurocognitive Performance: A Meta-Analytic Review of Randomized Controlled Trials
Patrick J. Smith et al.
PSYCHOSOMATIC MEDICINE (2010)
Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease
Alex E. Roher et al.
ALZHEIMERS & DEMENTIA (2009)
The Neuropathology of Probable Alzheimer Disease and Mild Cognitive Impairment
Julie A. Schneider et al.
ANNALS OF NEUROLOGY (2009)
FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease
Lisa Mosconi et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2009)
The influence of age on the association between cholesterol and cognitive function
Peter van Vliet et al.
EXPERIMENTAL GERONTOLOGY (2009)
Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease
Magali Dumont et al.
FASEB JOURNAL (2009)
Age Effects on the Regulation of Adult Hippocampal Neurogenesis by Physical Activity and Environmental Enrichment in the APP23 Mouse Model of Alzheimer Disease
Sebastian Mirochnic et al.
HIPPOCAMPUS (2009)
Cerebral blood flow during exercise: mechanisms of regulation
Shigehiko Ogoh et al.
JOURNAL OF APPLIED PHYSIOLOGY (2009)
Repression of Tau Hyperphosphorylation by Chronic Endurance Exercise in Aged Transgenic Mouse Model of Tauopathies
Yea-Hyun Leem et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Comparison of lifelong and late life exercise on oxidative stress in the cerebellum
Li Cui et al.
NEUROBIOLOGY OF AGING (2009)
Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease
Carla M. Yuede et al.
NEUROBIOLOGY OF DISEASE (2009)
Insulin Resistance and Hyperinsulinemia Is hyperinsulinemia the cart or the horse?
Michael H. Shanik et al.
DIABETES CARE (2008)
Systemic adaptation to oxidative challenge induced by regular exercise
Zsolt Radak et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system
Ryan N. Dilger et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
Kathryn E. Nichol et al.
JOURNAL OF NEUROINFLAMMATION (2008)
Elevation in cerebral blood flow velocity with aerobic fitness throughout healthy human ageing
Philip N. Ainslie et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Exercise Training and Plasma C-Reactive Protein and Interleukin-6 in Elderly People
Barbara J. Nicklas et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2008)
Physical activity, physical function, and incident dementia in elderly men: The Honolulu-Asia Aging Study
Dennis R. Taaffe et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)
Alzheimer's disease - Moving towards a vaccine
David M. Holtzman
NATURE (2008)
Exercise as a Mean to Control Low-Grade Systemic Inflammation
Neha Mathur et al.
MEDIATORS OF INFLAMMATION (2008)
Hippocampal hypornetabolism predicts cognitive decline from normal aging
Lisa Mosconi et al.
NEUROBIOLOGY OF AGING (2008)
Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
A. Parachikova et al.
NEUROBIOLOGY OF DISEASE (2008)
BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?
Yuan Lu et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2008)
Exercise-induced oxidative stress: Cellular mechanisms and impact on muscle force production
Scott K. Powers et al.
PHYSIOLOGICAL REVIEWS (2008)
Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology
Meizhang Li et al.
PROGRESS IN NEUROBIOLOGY (2008)
Effect of resistance training on immunological parameters of healthy elderly women
Vagner Raso et al.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2007)
Exercise builds brain health: key roles of growth factor cascades and inflammation (vol 9, pg 464, 2007)
Carl W. Cotman et al.
TRENDS IN NEUROSCIENCES (2007)
Inactivity, exercise training and detraining, and plasma lipoproteins. STRRIDE: a randomized, controlled study of exercise intensity and amount
Cris A. Slentz et al.
JOURNAL OF APPLIED PHYSIOLOGY (2007)
Chronic kidney disease - Effects on the cardiovascular system
Ernesto L. Schiffrin et al.
CIRCULATION (2007)
Forecasting the global burden of Alzheimer's disease
Ron Brookmeyer et al.
ALZHEIMERS & DEMENTIA (2007)
Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol - A meta-analysis
Satoru Kodama et al.
ARCHIVES OF INTERNAL MEDICINE (2007)
Habitual physical activity is associated with intrahepatic fat content in humans
Gianluca Perseghin et al.
DIABETES CARE (2007)
Oxidative stress mediates tau-induced neurodegeneration in Drosophila
Dora Dias-Santagata et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Exercise builds brain health: key roles of growth factor cascades and inflammation
Carl W. Cotman et al.
TRENDS IN NEUROSCIENCES (2007)
Regulation of cerebral blood flow during exercise
Jordan S. Querido et al.
SPORTS MEDICINE (2007)
Alzheimer disease, the two-hit hypothesis: An update
Xiongwei Zhu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2007)
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
Carlo Ballatore et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease
Susanne A. Wolf et al.
BIOLOGICAL PSYCHIATRY (2006)
Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau
D. R. Williams
INTERNAL MEDICINE JOURNAL (2006)
Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment
Chiara Rossi et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Heart failure and risk of dementia and Alzheimer disease - A population-based cohort study
Chengxuan Qiu et al.
ARCHIVES OF INTERNAL MEDICINE (2006)
Interleukin-6 in aging and chronic disease: A magnificent pathway
Marcello Maggio et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2006)
Risk of dementia in diabetes mellitus: a systematic review
GJ Biessels et al.
LANCET NEUROLOGY (2006)
Cognitive decline and dementia in diabetes - systematic overview of prospective observational studies
T Cukierman et al.
DIABETOLOGIA (2005)
The genetic epidemidogy of neurodegenerative disease
L Bertram et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
The effects of moderate-, strenuous- and over-training on oxidative stress markers, DNA repair, and memory, in rat brain
H Ogonovszky et al.
NEUROCHEMISTRY INTERNATIONAL (2005)
Post-translational modifications of tau protein in Alzheimer's disease
CX Gong et al.
JOURNAL OF NEURAL TRANSMISSION (2005)
Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease
PA Adlard et al.
JOURNAL OF NEUROSCIENCE (2005)
Macrophage inflammatory protein 2 inhibits β-amyloid peptide (1-42)-mediated hippocampal neuronal apoptosis through activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways
K Watson et al.
MOLECULAR PHARMACOLOGY (2005)
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes?
E Steen et al.
JOURNAL OF ALZHEIMERS DISEASE (2005)
AD lesions and infarcts in demented and non-demented Japanese-American men
H Petrovitch et al.
ANNALS OF NEUROLOGY (2005)
Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid β-protein
W Farris et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI
MD Greicius et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Exercise and hypertension
LS Pescatello et al.
MEDICINE & SCIENCE IN SPORTS & EXERCISE (2004)
Lipoxygenase-dependent superoxide release in skeletal muscle
L Zuo et al.
JOURNAL OF APPLIED PHYSIOLOGY (2004)
Comorbid type 2 diabetes mellitus and hypertension exacerbates cognitive decline: evidence from a longitudinal study
LB Hassing et al.
AGE AND AGEING (2004)
Oxidative stress in neurodegeneration: cause or consequence?
JK Andersen
NATURE MEDICINE (2004)
Physical activity, exercise, and inflammatory markers in older adults: Findings from the health, aging and body composition study
LH Colbert et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2004)
Change in cognitive function by glucose tolerance status in older adults - A 4-year prospective study of the Rancho Bernardo Study Cohort
AM Kanaya et al.
ARCHIVES OF INTERNAL MEDICINE (2004)
Cytokine changes in the horizontal diagonal band of broca in the septum after running and stroke: A correlation to glial activation
ET Ang et al.
NEUROSCIENCE (2004)
Influence of physical activity on serum IL-6 and IL-10 levels in healthy older men
R Jankord et al.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2004)
Systemic catabolism of Alzheimer's Aβ40 and Aβ42
J Ghiso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Brain insulin impairs amyloid-β(1-40) clearance from the brain
T Shiiki et al.
JOURNAL OF NEUROSCIENCE (2004)
Hyperinsulinemia and risk of Alzheimer disease
JA Luchsinger et al.
NEUROLOGY (2004)
Habitual exercise did not affect the balance of type 1 and type 2 cytokines in elderly people
K Ogawa et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Response of oxidative stress biomarkers to a 16-week aerobic physical activity program, and to acute physical activity, in healthy young men and women
R Elosua et al.
ATHEROSCLEROSIS (2003)
The role of insulin resistance in the pathogenesis of Alzheimer's disease - Implications for treatment
GS Watson et al.
CNS DRUGS (2003)
IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation
G Kaplanski et al.
TRENDS IN IMMUNOLOGY (2003)
Antioxidants as treatment for neurodegenerative disorders
B Moosmann et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2002)
Lipid peroxidation in aging brain and Alzheimer's disease
TJ Montine et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Risk factors for Alzheimer's disease:: A prospective analysis from the Canadian Study of Health and Aging
J Lindsay et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2002)
Oxidative stress increases expression and activity of BACE in NT2 neurons
E Tamagno et al.
NEUROBIOLOGY OF DISEASE (2002)
What is cognitive reserve? Theory and research application of the reserve concept
Y Stern
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY (2002)
Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus -: A meta-analysis of controlled clinical trials
NG Boulé et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)
Oxidative damage is the earliest event in Alzheimer disease
A Nunomura et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
Midlife vascular risk factors and Alzheimer's disease in later life:: longitudinal, population based study
M Kivipelto et al.
BMJ-BRITISH MEDICAL JOURNAL (2001)
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
E Kojro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Association between physical activity and markers of inflammation in a healthy elderly population
DF Geffken et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2001)
Regular exercise improves cognitive function and decreases oxidative damage in rat brain
Z Radak et al.
NEUROCHEMISTRY INTERNATIONAL (2001)
Exercise and the immune system: regulation, integration, and adaptation
BK Pedersen et al.
PHYSIOLOGICAL REVIEWS (2000)
Midlife blood pressure and dementia: the Honolulu-Asia aging study
LJ Launer et al.
NEUROBIOLOGY OF AGING (2000)
Share Paper
