Journal
INORGANIC CHEMISTRY
Volume 58, Issue 16, Pages 10616-10619Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.inorgchem.9b01900
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Funding
- Beneficentia Stiftung [19650]
- Ente Cassa Rismarmio Firenze [19650]
- Associazione Italiana per la Ricerca sul Cancro (AIRC) [19650]
- AIRC-Fondazione Italiana per la Ricerca sul Cancro (FIRC) [22587]
- AIRC [22294]
- Fondazione CR Firenze [22294]
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The medicinal gold(III) dithiocarbamato complex AuL12 forms a stable adduct with bovine serum albumin. The crystal structure reveals that a single gold(I) center is bound to Cys34, with the dithiocarbamato ligand being released. To the best of our knowledge, this is the first structure for a gold adduct of serum albumin.
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