Journal
IEEE TRANSACTIONS ON IMAGE PROCESSING
Volume 28, Issue 7, Pages 3584-3597Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TIP.2019.2899947
Keywords
Image registration; set distance; gradient methods; optimization; cost function; iterative algorithms; fuzzy sets; magnetic resonance imaging; transmission electron microscopy
Funding
- VINNOVA through MedTech4Health [2016-02329, 2017-02447]
- Swedish Research Council [2015-05878, 2017-04385]
- Ministry of Education, Science, and Technical Development of the Republic of Serbia [ON174008, III44006]
- Swedish Research Council [2017-04385, 2015-05878] Funding Source: Swedish Research Council
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Intensity-based image registration approaches rely on similarity measures to guide the search for geometric correspondences with the high affinity between images. The properties of the used measures are vital for the robustness and accuracy of the registration. In this paper, a symmetric, intensity interpolation-free, affine registration framework based on a combination of intensity and spatial information is proposed. The excellent performance of the framework is demonstrated on a combination of synthetic tests, recovering known transformations in the presence of noise, and real applications in biomedical and medical image registration, for both 2D and 3D images. The method exhibits greater robustness and higher accuracy than similarity measures in common use, when inserted into a standard gradient-based registration framework available as part of the open source Insight Segmentation and Registration Toolkit. The method is also empirically shown to have a low computational cost, making it practical for real applications. The source code is available.
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