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Metabolites from nematophagous fungi and nematicidal natural products from fungi as alternatives for biological control. Part II: metabolites from nematophagous basidiomycetes and non-nematophagous fungi

Journal

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume 100, Issue 9, Pages 3813-3824

Publisher

SPRINGER
DOI: 10.1007/s00253-015-7234-5

Keywords

Phytoparasitic nematodes; Nematicides; Nematophagous fungi; Secondary metabolites; Biocontrol

Funding

  1. Hessian State Ministry of Higher Education, Research and the Arts (HMWK)

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In this second section of a two-part mini-review article, we introduce 101 further nematicidal and non-nematicidal secondary metabolites biosynthesized by nematophagous basidiomycetes or non-nematophagous ascomycetes and basidiomycetes. Several of these compounds have promising nematicidal activity and deserve further and more detailed analysis. Thermolides A and B, omphalotins, ophiobolins, bursaphelocides A and B, illinitone A, pseudohalonectrins A and B, dichomitin B, and caryopsomycins A-C are excellent candidates or lead compounds for the development of biocontrol strategies for phytopathogenic nematodes. Paraherquamides, clonostachydiol, and nafuredins offer promising leads for the development of formulations against the intestinal nematodes of ruminants.

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