4.4 Review

The influence of drugs on peripheral nerve regeneration

Journal

DRUG METABOLISM REVIEWS
Volume 51, Issue 3, Pages 266-292

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/03602532.2019.1632885

Keywords

Drugs; nerve; regeneration; peripheral nerves; remyelination

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Currently, there are no established adjuvant drugs for the acceleration of peripheral nerve regeneration. In this paper, we reviewed the literature from the last 10 years and described the drugs proved to accelerate the functional and histological regeneration of the peripheral nerves, either after trauma or in neuropathy experimental models. The vast majority of the studies were experimental with very few small clinical studies, which indicates the need for prospective randomized studies to identify the best drugs to use as adjuvants for nerve regeneration.

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