4.7 Article

Cyanostilbene-based near-infrared emissive platinum(II) metallacycles for cancer theranostics

Journal

CHINESE CHEMICAL LETTERS
Volume 30, Issue 11, Pages 1942-1946

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2019.07.043

Keywords

Near-infrared emission; Self-assembly; Metallacycles; Cancer therapy; Cell imaging

Funding

  1. National Natural Science Foundation of China [21801203]
  2. Key Research and Development Program of Shaanxi Province [2019KW-019, 2019KW-066]
  3. Xi'an Jiaotong University

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In this work, a near-infrared emissive dipyridyl ligand was synthesized and used to prepare three platinum(II) metallacycles with different shapes via metal-coordination-driven self-assembly with different platinum(II) precursors. These metallacycles were further used for both cell imaging and cancer therapy, offering a new type of theranostic agents towards cancer treatment. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

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