Photochemical Hydroacylation of Michael Acceptors Utilizing an Aldehyde as Photoinitiator

The hydroacylation of Michael acceptors constitutes a useful tool for the formation of new C-C bonds. In this work, an environmentally friendly procedure was developed, utilizing 4cyanobenzaldehyde as the photoinitiator and household bulbs as the irradiation source. A great variety of substrates was well-tolerated, leading to good yields, and mechanistic experiments were performed to elucidate the catalyst's possible mechanistic pathway. Moreover, the inherent selectivity challenge regarding alpha,alpha-disubstituted aldehydes (decarbonylation problem) was studied and addressed.