4.7 Review

The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases

Journal

BIOMEDICINE & PHARMACOTHERAPY
Volume 114, Issue -, Pages -

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2019.108846

Keywords

Fuzheng Huayu; Chronic liver disease; Clinical application; Antifibrotic effect; Mechanism

Funding

  1. National Natural Science Foundation of China [81530101]

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Fuzheng Huayu formula (FZHY) is a traditional Chinese medicine formula composed of Radix Salvia Miltiorrhizae, Cordyceps, Semen Persicae, Gynostemma Pentaphyllammak, Pollen Pini, Fructus Schisandrae Chinensis that is used to treat chronic liver diseases in China. We here describe the pharmacological actions of FZHY in this review. We also describe and provide updates on recent advances in the medical applications and the basic research of mechanisms of FZHY formula. FZHY has been shown to have no serious adverse reactions and exerts antifibrotic effects through targeting more than one molecule.

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