Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 63, Issue 9, Pages -Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00809-19
Keywords
Enterococcus faecalis; optrA; oxazolidinones; phenicols; transposon
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Funding
- National Natural Science Foundation of China [U1604103]
- Program for Innovative Research Team (in Science and Technology) in University of Henan Province [18IRTSTHN020]
- German Federal Ministry of Education and Research (BMBF), Research Network Zoonotic Infectious Diseases [01KI1727D]
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The novel 12,932-bp nonconjugative multiresistance transposon Tn6674 was identified in the chromosomal DNA of a porcine Enterococcus faecalis strain. Tn6674 belongs to the Tn554 family of transposons. It shares the same arrangement of the transposase genes tnpA, tnpB, and tnpC with Tn554. However, in addition to the Tn554-associated resistance genes spc and erm(A), Tn6674 harbored the resistance genes fexA and optrA. Circular forms of Tn6674 were detected and suggest the functional activity of this transposon.
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