4.7 Review

Standards for Detecting, Interpreting, and Reporting Noncontrast Computed Tomographic Markers of Intracerebral Hemorrhage Expansion

Journal

ANNALS OF NEUROLOGY
Volume 86, Issue 4, Pages 480-492

Publisher

WILEY
DOI: 10.1002/ana.25563

Keywords

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Funding

  1. Heart and Stroke Foundation of Canada Clinician-Scientist Award
  2. National Key Research and Development Program of China [2018YFC1312200, 2018YFC1312203]
  3. National Health and Family Planning Commission of Chongqing [2017MSXM014]
  4. China Association for Science and Technology Young Talent Project [2017QNRC001]
  5. University of New South Wales, Sydney
  6. NovoNordisk Canada
  7. MRC [G1002605] Funding Source: UKRI

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Significant hematoma expansion (HE) affects one-fifth of people within 24 hours after acute intracerebral hemorrhage (ICH), and its prevention is an appealing treatment target. Although the computed tomography (CT)-angiography spot sign predicts HE, only a minority of ICH patients receive contrast injection. Conversely, noncontrast CT (NCCT) is used to diagnose nearly all ICH, so NCCT markers represent a widely available alternative for prediction of HE. However, different NCCT signs describe similar features, with lack of consensus on the optimal image acquisition protocol, assessment, terminology, and diagnostic criteria. In this review, we propose practical guidelines for detecting, interpreting, and reporting NCCT predictors of HE. ANN NEUROL 2019

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