4.8 Review

Polymer Fiber Scaffolds for Bone and Cartilage Tissue Engineering

Journal

ADVANCED FUNCTIONAL MATERIALS
Volume 29, Issue 36, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adfm.201903279

Keywords

3D scaffolds; bone regeneration; cartilage repair; osteochondral tissue engineering; polymer fibers

Funding

  1. National Natural Science Foundation of China [51873207, 51803006, 51833010, 81671785, 51673190, 51603204, 51673187, 51520105004]
  2. Science and Technology Development Program of Jilin Province [20190201068JC]
  3. Research Program for Young and Middle-Aged Teachers of Fujian Province [JT180039]
  4. National Key Research and Development Program of China [2016YFC1100701]

Ask authors/readers for more resources

Successful regeneration of weight-bearing bone defects and critical-sized cartilage defects remains a major challenge in clinical orthopedics. In the past decades, biodegradable polymer materials with biomimetic chemical and physical properties have been rapidly developed as ideal candidates for bone and cartilage tissue engineering scaffolds. Due to their unique advantages over other materials of high specific-surface areas, suitable mechanical strength, and tailorable characteristics, scaffolds made of polymer fibers have been increasingly used for the repair of bone and cartilage defects. This Review summarizes the preparation and compositions of polymer fibers, as well as their characteristics. More importantly, the applications of polymer fiber scaffolds with well-designed structures or unique properties in bone, cartilage, and osteochondral tissue engineering have been comprehensively highlighted. On the whole, such a comprehensive summary affords constructive suggestions for the development of polymer fiber scaffolds in bone and cartilage tissue engineering.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available